| Protein Name | lysine acetyltransferase 2B |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 8850 |
| Gene Symbol | KAT2B |
| UniProt | Q92831 (KAT2B_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
295
Total Number of Articles : 373 |
Description |
lysine acetyltransferase 2B |
| Gene Summary |
CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation. [provided by RefSeq, Jul 2008] |
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