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34043345 | Bavachinin Induces G2/M Cell Cycle Arrest and Apoptosis via the ATM/ATR Signaling Pathway in Human Small Cell Lung Cancer and Shows an Antitumor Effect in the Xenograft Model. | 2021 Jun 9 |
1 |
| 2 |
34324416 | A subset of CB002 xanthine analogs bypass p53-signaling to restore a p53 transcriptome and target an S-phase cell cycle checkpoint in tumors with mutated-p53. | 2021 Jul 29 |
1 |
| 3 |
28986085 | Ovatodiolide isolated from Anisomeles indica induces cell cycle G2/M arrest and apoptosis via a ROS-dependent ATM/ATR signaling pathways. | 2018 Jan 15 |
1 |
| 4 |
26683224 | Galiellalactone induces cell cycle arrest and apoptosis through the ATM/ATR pathway in prostate cancer cells. | 2016 Jan 26 |
1 |
| 5 |
26727128 | Checkpoint Kinase 1 Activation Enhances Intestinal Epithelial Barrier Function via Regulation of Claudin-5 Expression. | 2016 |
1 |
| 6 |
27797824 | A genome-wide analysis of gene-caffeine consumption interaction on basal cell carcinoma. | 2016 Dec |
1 |
| 7 |
25812484 | Resveratrol analogue (E)-8-acetoxy-2-[2-(3,4-diacetoxyphenyl)ethenyl]-quinazoline induces G₂/M cell cycle arrest through the activation of ATM/ATR in human cervical carcinoma HeLa cells. | 2015 May |
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| 8 |
26019182 | Caffeine impairs resection during DNA break repair by reducing the levels of nucleases Sae2 and Dna2. | 2015 Aug 18 |
1 |
| 9 |
26556501 | Effect of ATM and HDAC Inhibition on Etoposide-Induced DNA Damage in Porcine Early Preimplantation Embryos. | 2015 |
1 |
| 10 |
24380689 | Gap-filling and bypass at the replication fork are both active mechanisms for tolerance of low-dose ultraviolet-induced DNA damage in the human genome. | 2014 Feb |
1 |
| 11 |
24972086 | Kaposi sarcoma herpes virus latency associated nuclear antigen protein release the G2/M cell cycle blocks by modulating ATM/ATR mediated checkpoint pathway. | 2014 |
1 |
| 12 |
25530717 | Induction of H2AX phosphorylation in tumor cells by gossypol acetic acid is mediated by phosphatidylinositol 3-kinase (PI3K) family. | 2014 |
2 |
| 13 |
23733185 | 4-Hydroxynonenal induces G2/M phase cell cycle arrest by activation of the ataxia telangiectasia mutated and Rad3-related protein (ATR)/checkpoint kinase 1 (Chk1) signaling pathway. | 2013 Jul 12 |
2 |
| 14 |
21964066 | The p53-p21WAF1 checkpoint pathway plays a protective role in preventing DNA rereplication induced by abrogation of FOXF1 function. | 2012 Jan |
2 |
| 15 |
22753029 | CHK1 activity is required for continuous replication fork elongation but not stabilization of post-replicative gaps after UV irradiation. | 2012 Sep 1 |
1 |
| 16 |
23096362 | Response of the G2-prophase checkpoint to genotoxic drugs in lymphocytes from healthy individuals. | 2012 |
1 |
| 17 |
21308861 | Inhibition of ataxia telangiectasia- and Rad3-related function abrogates the in vitro and in vivo tumorigenicity of human colon cancer cells through depletion of the CD133(+) tumor-initiating cell fraction. | 2011 Mar |
2 |
| 18 |
21336968 | Chk1 has an essential role in the survival of differentiated cortical neurons in the absence of DNA damage. | 2011 May |
1 |
| 19 |
21561856 | Caffeine promotes ultraviolet B-induced apoptosis in human keratinocytes without complete DNA repair. | 2011 Jul 1 |
1 |
| 20 |
20028385 | Hydroxyurea upregulates NKG2D ligand expression in myeloid leukemia cells synergistically with valproic acid and potentially enhances susceptibility of leukemic cells to natural killer cell-mediated cytolysis. | 2010 Mar |
1 |
| 21 |
20861183 | Evidence of an adaptive response targeting DNA nonhomologous end joining and its transmission to bystander cells. | 2010 Nov 1 |
1 |
| 22 |
19098271 | ATM-ATR-dependent up-regulation of DNAM-1 and NKG2D ligands on multiple myeloma cells by therapeutic agents results in enhanced NK-cell susceptibility and is associated with a senescent phenotype. | 2009 Apr 9 |
2 |
| 23 |
19242509 | ATR-Chk1 pathway inhibition promotes apoptosis after UV treatment in primary human keratinocytes: potential basis for the UV protective effects of caffeine. | 2009 Jul |
3 |
| 24 |
19261750 | Bifunctional DNA alkylator 1,3-bis(2-chloroethyl)-1-nitrosourea activates the ATR-Chk1 pathway independently of the mismatch repair pathway. | 2009 Jun |
1 |
| 25 |
19262568 | Rad52 recruitment is DNA replication independent and regulated by Cdc28 and the Mec1 kinase. | 2009 Apr 22 |
1 |
| 26 |
19296337 | Stress response of a p53 homologue in the radioresistant Sf9 insect cells. | 2009 Mar |
1 |
| 27 |
19364474 | Cell cycle arrest triggered by conjugated eicosapentaenoic acid occurs through several mechanisms including G1 checkpoint activation by induced RPA and ATR expression. | 2009 May |
1 |
| 28 |
19414815 | Proteasome regulation of ULBP1 transcription. | 2009 May 15 |
1 |
| 29 |
19738435 | Cancer stem cells and escape from drug-induced premature senescence in human lung tumor cells: implications for drug resistance and in vitro drug screening models. | 2009 Oct 1 |
1 |
| 30 |
19903334 | The ATM and ATR inhibitors CGK733 and caffeine suppress cyclin D1 levels and inhibit cell proliferation. | 2009 Nov 10 |
1 |
| 31 |
18440285 | Sustained activation of p53 in confluent nucleotide excision repair-deficient cells resistant to ultraviolet-induced apoptosis. | 2008 Jun 1 |
1 |
| 32 |
18946034 | Human DNA polymerase eta activity and translocation is regulated by phosphorylation. | 2008 Oct 28 |
1 |
| 33 |
19004803 | ATR kinase is required for global genomic nucleotide excision repair exclusively during S phase in human cells. | 2008 Nov 18 |
1 |
| 34 |
17167777 | Activation of the S phase DNA damage checkpoint by mitomycin C. | 2007 May |
1 |
| 35 |
17283049 | Glycogen synthase kinase 3beta phosphorylates p21WAF1/CIP1 for proteasomal degradation after UV irradiation. | 2007 Apr |
1 |
| 36 |
17297454 | Irradiation-induced G2/M checkpoint response requires ERK1/2 activation. | 2007 Jul 12 |
1 |
| 37 |
17468739 | DNA damage induces Chk1-dependent centrosome amplification. | 2007 Jun |
1 |
| 38 |
17726372 | DNA damage-induced accumulation of centrosomal Chk1 contributes to its checkpoint function. | 2007 Oct 15 |
1 |
| 39 |
16690369 | Menin localizes to chromatin through an ATR-CHK1 mediated pathway after UV-induced DNA damage. | 2006 Jun 1 |
2 |
| 40 |
16741947 | ATR dependent activation of Chk2. | 2006 Sep |
2 |
| 41 |
16908529 | ATR-dependent phosphorylation of DNA-dependent protein kinase catalytic subunit in response to UV-induced replication stress. | 2006 Oct |
1 |
| 42 |
17026965 | Single-stranded oligonucleotide-mediated gene repair in mammalian cells has a mechanism distinct from homologous recombination repair. | 2006 Nov 24 |
1 |
| 43 |
15709017 | DNA damage sensors ATM, ATR, DNA-PKcs, and PARP-1 are dispensable for human immunodeficiency virus type 1 integration. | 2005 Mar |
1 |
| 44 |
15831461 | Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage. | 2005 May |
1 |
| 45 |
15840517 | Inhibition of HIV-1 replication by caffeine and caffeine-related methylxanthines. | 2005 May 10 |
2 |
| 46 |
15975956 | Resveratrol causes Cdc2-tyr15 phosphorylation via ATM/ATR-Chk1/2-Cdc25C pathway as a central mechanism for S phase arrest in human ovarian carcinoma Ovcar-3 cells. | 2005 Nov |
2 |
| 47 |
15994368 | N-methyl-N'-nitro-N-nitrosoguanidine activates cell-cycle arrest through distinct mechanisms activated in a dose-dependent manner. | 2005 Oct |
1 |
| 48 |
16014567 | Tachpyridine, a metal chelator, induces G2 cell-cycle arrest, activates checkpoint kinases, and sensitizes cells to ionizing radiation. | 2005 Nov 1 |
1 |
| 49 |
16238096 | Roles of nibrin and AtM/ATR kinases on the G2 checkpoint under endogenous or radio-induced DNA damage. | 2005 |
1 |
| 50 |
14716295 | The EBNA-3 gene family proteins disrupt the G2/M checkpoint. | 2004 Feb 19 |
1 |