triptolide


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837 Functionally related protein(s)
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Protein Name
UniProt Entry
Gene Symbol
Organism
NCBI Gene ID
# All related compound(s)
#Article(s)
1 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 39
2 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 35
3 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 32
4 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 32
5 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 29
6 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 NFKB1_MOUSE Nfkb1 Mus musculus 18033 3161 21
7 tumor necrosis factor TNFA_MOUSE Tnf Mus musculus 21926 5931 21
8 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 20
9 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 20
10 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 18
11 interleukin 6 IL6_MOUSE Il6 Mus musculus 16193 3985 17
12 tumor necrosis factor TNFA_RAT Tnf Rattus norvegicus 24835 3922 17
13 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 16
14 NFE2 like bZIP transcription factor 2 NF2L2_HUMAN NFE2L2 Homo sapiens 4780 2545 15
15 dual specificity phosphatase 1 DUS1_HUMAN DUSP1 Homo sapiens 1843 284 15
16 heat shock protein family A (Hsp70) member 4 HSP74_HUMAN HSPA4 Homo sapiens 3308 1053 14
17 MCL1 apoptosis regulator, BCL2 family member MCL1_HUMAN MCL1 Homo sapiens 4170 1015 14
18 interleukin 10 IL10_MOUSE Il10 Mus musculus 16153 1965 12
19 transforming growth factor, beta 1 TGFB1_MOUSE Tgfb1 Mus musculus 21803 1658 12
20 interleukin 6 IL6_RAT Il6 Rattus norvegicus 24498 2269 11
21 interferon gamma IFNG_HUMAN IFNG Homo sapiens 3458 3371 11
22 mitogen-activated protein kinase 14 MK14_MOUSE Mapk14 Mus musculus 26416 2012 11
23 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 11
24 v-rel reticuloendotheliosis viral oncogene homolog A (avian) TF65_MOUSE Rela Mus musculus 19697 993 11
25 caspase 9 CASP9_HUMAN CASP9 Homo sapiens 842 1801 11
26 caspase 8 CASP8_HUMAN CASP8 Homo sapiens 841 1641 10
27 RELA proto-oncogene, NF-kB subunit TF65_HUMAN RELA Homo sapiens 5970 1514 10
28 TNF superfamily member 10 TNF10_HUMAN TNFSF10 Homo sapiens 8743 1439 10
29 transforming growth factor, beta 1 TGFB1_RAT Tgfb1 Rattus norvegicus 59086 1730 10
30 nuclear factor, erythroid derived 2, like 2 NF2L2_MOUSE Nfe2l2 Mus musculus 18024 2012 10
31 MYC proto-oncogene, bHLH transcription factor MYC_HUMAN MYC Homo sapiens 4609 2261 10
32 thymoma viral proto-oncogene 1 AKT1_MOUSE Akt1 Mus musculus 11651 3034 9
33 NFKB inhibitor alpha IKBA_HUMAN NFKBIA Homo sapiens 4792 1043 9
34 mitogen-activated protein kinase 8 MK08_HUMAN MAPK8 Homo sapiens 5599 2863 9
35 catenin beta 1 CTNB1_HUMAN CTNNB1 Homo sapiens 1499 2350 9
36 cytochrome c, somatic CYC_HUMAN CYCS Homo sapiens 54205 3740 9
37 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 9
38 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 9
39 interleukin 1 beta Q5BKB0_RAT Il1b Rattus norvegicus 24494 2252 9
40 prostaglandin-endoperoxide synthase 2 PGH2_HUMAN PTGS2 Homo sapiens 5743 2572 9
41 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 9
42 mitogen-activated protein kinase 8 MK08_MOUSE Mapk8 Mus musculus 26419 1537 9
43 mitogen-activated protein kinase 1 MK01_MOUSE Mapk1 Mus musculus 26413 1992 8
44 dual specificity phosphatase 1 DUS1_MOUSE Dusp1 Mus musculus 19252 153 8
45 toll-like receptor 4 TLR4_MOUSE Tlr4 Mus musculus 21898 2266 8
46 X-linked inhibitor of apoptosis XIAP_HUMAN XIAP Homo sapiens 331 647 8
47 interleukin 1 beta IL1B_MOUSE Il1b Mus musculus 16176 2626 8
48 caspase 3 CASP3_MOUSE Casp3 Mus musculus 12367 1791 8
49 interferon gamma IFNG_MOUSE Ifng Mus musculus 15978 2936 8
50 cytochrome P450, family 3, subfamily a, polypeptide 62 Q8CJF2_RAT Cyp3a62 Rattus norvegicus 170509 585 8