triptolide

BCL2 apoptosis regulator ; Homo sapiens







20 Article(s)
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1 34915630 [Triptolide increases the radiosensitivity of lung cancer cells by inhibiting DNA repair and inducing apoptosis]. 2021 Dec 23 1
2 32699295 Combining triptolide with ABT-199 is effective against acute myeloid leukemia through reciprocal regulation of Bcl-2 family proteins and activation of the intrinsic apoptotic pathway. 2020 Jul 22 2
3 32733649 Triptolide-induced apoptosis in non-small cell lung cancer via a novel miR204-5p/Caveolin-1/Akt-mediated pathway. 2020 Jul 14 1
4 31115521 Triptolide exerts an anti-tumor effect on non‑small cell lung cancer cells by inhibiting activation of the IL‑6/STAT3 axis. 2019 Jul 1
5 27879593 Triptolide Reduces the Required Dose of Tacrolimus by Attenuating Inflammation, Enhancing Immunosuppression, and Increasing Donor Chimerism in a Heterotopic Hindlimb Transplantation Model. 2016 Dec 1
6 27999372 Triptolide Combined with Radiotherapy for the Treatment of Nasopharyngeal Carcinoma via NF-κB-Related Mechanism. 2016 Dec 19 1
7 25573072 Combination treatment with triptolide and hydroxycamptothecin synergistically enhances apoptosis in A549 lung adenocarcinoma cells through PP2A-regulated ERK, p38 MAPKs and Akt signaling pathways. 2015 Mar 1
8 25875797 Primary and liver metastasis-derived cell lines from KrasG12D; Trp53R172H; Pdx-1 Cre animals undergo apoptosis in response to triptolide. 2015 May 1
9 26107205 The Inhibition Effect of Triptolide on Human Endometrial Carcinoma Cell Line HEC-1B: a in vitro and in vivo Studies. 2015 1
10 24566325 Triptolide induces s phase arrest and apoptosis in gallbladder cancer cells. 2014 Feb 24 3
11 24880464 Selective tumor cell killing by triptolide in p53 wild-type and p53 mutant ovarian carcinomas. 2014 Jul 1
12 23900299 Triptolide induces apoptosis of PMA-treated THP-1 cells through activation of caspases, inhibition of NF-κB and activation of MAPKs. 2013 Oct 1
13 24772972 Triptolide induces apoptosis through extrinsic and intrinsic pathways in human osteosarcoma U2OS cells. 2013 Dec 1
14 19903580 Triptolide simultaneously induces reactive oxygen species, inhibits NF-kappaB activity and sensitizes 5-fluorouracil in colorectal cancer cell lines. 2010 May 28 1
15 19942343 Triptolide inhibits Jak2 transcription and induces apoptosis in human myeloproliferative disorder cells bearing Jak2V617F through caspase-3-mediated cleavage of Mcl-1. 2010 May 28 1
16 18379047 Involvement of mitochondrial pathway in triptolide-induced cytotoxicity in human normal liver L-02 cells. 2008 Apr 1
17 17900403 The effect of triptolide on apoptosis of glioblastoma multiforme (GBM) cells. 2007 Sep-Oct 1
18 16316721 Triptolide induces Bcl-2 cleavage and mitochondria dependent apoptosis in p53-deficient HL-60 cells. 2006 Sep 8 5
19 16385419 Mechanism of triptolide-induced apoptosis: Effect on caspase activation and Bid cleavage and essentiality of the hydroxyl group of triptolide. 2006 May 1
20 12508653 [Several monomes from Tripterygium wilfordii inhibit proliferation of glioma cells in vitro]. 2002 Oct 2