triptolide

caspase 3 ; Homo sapiens







32 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34094678 Minnelide, a prodrug, inhibits cervical cancer growth by blocking HPV-induced changes in p53 and pRb. 2021 1
2 34108030 Natural product triptolide induces GSDME-mediated pyroptosis in head and neck cancer through suppressing mitochondrial hexokinase-ΙΙ. 2021 Jun 9 2
3 34915630 [Triptolide increases the radiosensitivity of lung cancer cells by inhibiting DNA repair and inducing apoptosis]. 2021 Dec 23 1
4 31342801 Autophagy in Triptolide-Mediated Cytotoxicity in Hepatic Cells. 2019 Sep/Oct 1
5 29545863 Triptolide induces autophagy and apoptosis through ERK activation in human breast cancer MCF-7 cells. 2018 Apr 1
6 30563138 Triptolide Decreases Cell Proliferation and Induces Cell Death in Triple Negative MDA-MB-231 Breast Cancer Cells. 2018 Dec 5 1
7 26847601 Triptolide reduces proliferation and enhances apoptosis of human non-small cell lung cancer cells through PTEN by targeting miR-21. 2016 Mar 1
8 26935527 Triptolide sensitizes human breast cancer cells to tumor necrosis factor‑α‑induced apoptosis by inhibiting activation of the nuclear factor‑κB pathway. 2016 Apr 1
9 27461934 Triptolide induces the cell apoptosis of osteosarcoma cells through the TRAIL pathway. 2016 Sep 3
10 25573072 Combination treatment with triptolide and hydroxycamptothecin synergistically enhances apoptosis in A549 lung adenocarcinoma cells through PP2A-regulated ERK, p38 MAPKs and Akt signaling pathways. 2015 Mar 1
11 26161259 Triptolide potentiates lung cancer cells to cisplatin-induced apoptosis by selectively inhibiting the NER activity. 2015 1
12 24481531 Triptolide induces apoptotic cell death of multiple myeloma cells via transcriptional repression of Mcl-1. 2014 Apr 1
13 24566325 Triptolide induces s phase arrest and apoptosis in gallbladder cancer cells. 2014 Feb 24 3
14 24880464 Selective tumor cell killing by triptolide in p53 wild-type and p53 mutant ovarian carcinomas. 2014 Jul 1
15 23900299 Triptolide induces apoptosis of PMA-treated THP-1 cells through activation of caspases, inhibition of NF-κB and activation of MAPKs. 2013 Oct 1
16 24137468 Triptolide avoids cisplatin resistance and induces apoptosis via the reactive oxygen species/nuclear factor-κB pathway in SKOV3PT platinum-resistant human ovarian cancer cells. 2013 Oct 1
17 24309928 Triptolide induces apoptosis in human leukemia cells through caspase-3-mediated ROCK1 activation and MLC phosphorylation. 2013 Dec 5 1
18 25945102 Triptolide-Mediated Apoptosis by Suppression of Focal Adhesion Kinase through Extrinsic and Intrinsic Pathways in Human Melanoma Cells. 2013 1
19 21213403 In vitro synergistic cytotoxic effect of triptolide combined with hydroxycamptothecin on pancreatic cancer cells. 2011 1
20 21640813 Cytotoxicity of Triptolide and Triptolide loaded polymeric micelles in vitro. 2011 Dec 1
21 19903580 Triptolide simultaneously induces reactive oxygen species, inhibits NF-kappaB activity and sensitizes 5-fluorouracil in colorectal cancer cell lines. 2010 May 28 1
22 19942343 Triptolide inhibits Jak2 transcription and induces apoptosis in human myeloproliferative disorder cells bearing Jak2V617F through caspase-3-mediated cleavage of Mcl-1. 2010 May 28 2
23 20013316 TRAIL and triptolide: an effective combination that induces apoptosis in pancreatic cancer cells. 2010 Feb 1
24 20523343 Effects of triptolide on RIZ1 expression, proliferation, and apoptosis in multiple myeloma U266 cells. 2010 Jun 1
25 18379047 Involvement of mitochondrial pathway in triptolide-induced cytotoxicity in human normal liver L-02 cells. 2008 Apr 1
26 17468978 Involvement of PDCD5 in the regulation of apoptosis in fibroblast-like synoviocytes of rheumatoid arthritis. 2007 Aug 1
27 17699869 Enhanced antitumor effect of combined triptolide and ionizing radiation. 2007 Aug 15 1
28 17909050 Triptolide induces pancreatic cancer cell death via inhibition of heat shock protein 70. 2007 Oct 1 1
29 16385419 Mechanism of triptolide-induced apoptosis: Effect on caspase activation and Bid cleavage and essentiality of the hydroxyl group of triptolide. 2006 May 1
30 15972136 [Study of triptolide-induced apoptosis in MUTZ-1 cells and its allied mechanism]. 2005 Jun 2
31 12826269 Immunosuppressant PG490 (triptolide) induces apoptosis through the activation of caspase-3 and down-regulation of XIAP in U937 cells. 2003 Jul 15 4
32 12587840 Synergistic cytotoxicity and apoptosis induced in human cholangiocarcinoma cell lines by a combined treatment with tumor necrosis factor-alpha (TNF-alpha) and triptolide. 2002 Sep 2