Protein Name interleukin 10
Organism Mus musculus
Gene ID 16153
Gene Symbol


UniProt P18893 (IL10_MOUSE), Q3U879 (Q3U879_MOUSE)
Relationships Total Number of functionally related compound(s) : 1965
Total Number of Articles : 3267

interleukin 10

Gene Summary

This gene encodes an anti-inflammatory cytokine that is a member of the class-2 cytokine family. The encoded protein is secreted by cells of both the innate and adaptive immune systems and is crucial for limiting the immune response to a broad range of pathogens. It also has been shown to suppress autoimmune responses. This protein mediates it's immunosuppressive signal through a specific interleukin 10 receptor complex. Aberrant functioning of this gene is associated with numerous immune disorders including graft-versus-host disease, and increased susceptibility to HIV-1 infection and rheumatoid arthritis. [provided by RefSeq, Sep 2015]

  • interleukin-10
  • cytokine synthesis inhibitory factor
  • interferon 2a
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