| Protein Name | interleukin 10 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 16153 |
| Gene Symbol | Il10 |
| UniProt | P18893 (IL10_MOUSE), Q3U879 (Q3U879_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
1965
Total Number of Articles : 3267 |
Description |
interleukin 10 |
| Gene Summary |
This gene encodes an anti-inflammatory cytokine that is a member of the class-2 cytokine family. The encoded protein is secreted by cells of both the innate and adaptive immune systems and is crucial for limiting the immune response to a broad range of pathogens. It also has been shown to suppress autoimmune responses. This protein mediates it's immunosuppressive signal through a specific interleukin 10 receptor complex. Aberrant functioning of this gene is associated with numerous immune disorders including graft-versus-host disease, and increased susceptibility to HIV-1 infection and rheumatoid arthritis. [provided by RefSeq, Sep 2015] |
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