shikonin


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380 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 30
2 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 19
3 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 18
4 pyruvate kinase M1/2 KPYM_HUMAN PKM Homo sapiens 5315 441 16
5 receptor interacting serine/threonine kinase 1 RIPK1_HUMAN RIPK1 Homo sapiens 8737 356 13
6 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 12
7 tumor necrosis factor TNFA_MOUSE Tnf Mus musculus 21926 5931 11
8 pyruvate kinase, muscle KPYM_MOUSE Pkm Mus musculus 18746 157 10
9 mitogen-activated protein kinase 8 MK08_HUMAN MAPK8 Homo sapiens 5599 2863 9
10 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 9
11 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 9
12 mitogen-activated protein kinase 14 MK14_HUMAN MAPK14 Homo sapiens 1432 3132 9
13 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 9
14 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 8
15 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 8
16 receptor interacting serine/threonine kinase 3 RIPK3_HUMAN RIPK3 Homo sapiens 11035 184 8
17 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 7
18 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 NFKB1_MOUSE Nfkb1 Mus musculus 18033 3161 7
19 AKT serine/threonine kinase 1 AKT1_RAT Akt1 Rattus norvegicus 24185 2385 7
20 NFE2 like bZIP transcription factor 2 NF2L2_HUMAN NFE2L2 Homo sapiens 4780 2545 6
21 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 6
22 interleukin 6 IL6_MOUSE Il6 Mus musculus 16193 3985 6
23 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 6
24 caspase 9 CASP9_HUMAN CASP9 Homo sapiens 842 1801 6
25 caspase 8 CASP8_HUMAN CASP8 Homo sapiens 841 1641 6
26 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 6
27 interleukin 1 beta IL1B_MOUSE Il1b Mus musculus 16176 2626 5
28 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 5
29 cytochrome c, somatic CYC_HUMAN CYCS Homo sapiens 54205 3740 5
30 matrix metallopeptidase 2 MMP2_HUMAN MMP2 Homo sapiens 4313 2342 5
31 matrix metallopeptidase 9 MMP9_HUMAN MMP9 Homo sapiens 4318 2470 5
32 hypoxia inducible factor 1 subunit alpha HIF1A_HUMAN HIF1A Homo sapiens 3091 2152 5
33 BCL2-associated X protein BAX_MOUSE Bax Mus musculus 12028 1197 4
34 interleukin 17A IL17_HUMAN IL17A Homo sapiens 3605 977 4
35 H3 histone pseudogene 16 - H3P16 Homo sapiens 644914 2095 4
36 BCL2 like 1 B2CL1_HUMAN BCL2L1 Homo sapiens 598 1360 4
37 BCL2, apoptosis regulator BCL2_RAT Bcl2 Rattus norvegicus 24224 1676 4
38 caspase 3 CASP3_RAT Casp3 Rattus norvegicus 25402 2178 4
39 mixed lineage kinase domain like pseudokinase MLKL_HUMAN MLKL Homo sapiens 197259 160 4
40 BCL2 associated X, apoptosis regulator G3V8T9_RAT Bax Rattus norvegicus 24887 1472 4
41 mitogen-activated protein kinase 14 MK14_MOUSE Mapk14 Mus musculus 26416 2012 3
42 prostaglandin-endoperoxide synthase 2 PGH2_HUMAN PTGS2 Homo sapiens 5743 2572 3
43 caspase 3 CASP3_MOUSE Casp3 Mus musculus 12367 1791 3
44 prostaglandin-endoperoxide synthase 2 PGH2_MOUSE Ptgs2 Mus musculus 19225 1538 3
45 toll-like receptor 4 TLR4_MOUSE Tlr4 Mus musculus 21898 2266 3
46 TNF superfamily member 10 TNF10_HUMAN TNFSF10 Homo sapiens 8743 1439 3
47 nucleoporin 62 NUP62_HUMAN NUP62 Homo sapiens 23636 610 3
48 cadherin 1 CADH1_HUMAN CDH1 Homo sapiens 999 1360 3
49 tumor necrosis factor TNFA_RAT Tnf Rattus norvegicus 24835 3922 3
50 cytochrome b-245 beta chain CY24B_HUMAN CYBB Homo sapiens 1536 409 3