Temozolomide


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1349 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 O-6-methylguanine-DNA methyltransferase MGMT_HUMAN MGMT Homo sapiens 4255 549 746
2 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 100
3 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 76
4 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 70
5 isocitrate dehydrogenase (NADP(+)) 1 IDHC_HUMAN IDH1 Homo sapiens 3417 432 48
6 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 43
7 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 39
8 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 37
9 O-6-methylguanine-DNA methyltransferase MGMT_MOUSE Mgmt Mus musculus 17314 124 36
10 catenin beta 1 CTNB1_HUMAN CTNNB1 Homo sapiens 1499 2350 35
11 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 32
12 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 31
13 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 30
14 mutS homolog 6 MSH6_HUMAN MSH6 Homo sapiens 2956 127 23
15 poly (ADP-ribose) polymerase family, member 1 Q921K2_MOUSE Parp1 Mus musculus 11545 842 22
16 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 19
17 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 18
18 phosphatase and tensin homolog PTEN_HUMAN PTEN Homo sapiens 5728 1316 18
19 interferon beta 1 IFNB_HUMAN IFNB1 Homo sapiens 3456 620 17
20 ATM serine/threonine kinase ATM_HUMAN ATM Homo sapiens 472 847 17
21 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 17
22 hypoxia inducible factor 1 subunit alpha HIF1A_HUMAN HIF1A Homo sapiens 3091 2152 16
23 MYC proto-oncogene, bHLH transcription factor MYC_HUMAN MYC Homo sapiens 4609 2261 16
24 NFE2 like bZIP transcription factor 2 NF2L2_HUMAN NFE2L2 Homo sapiens 4780 2545 16
25 N-methylpurine DNA glycosylase 3MG_HUMAN MPG Homo sapiens 4350 446 15
26 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 14
27 mutL homolog 1 MLH1_HUMAN MLH1 Homo sapiens 4292 236 14
28 matrix metallopeptidase 2 MMP2_HUMAN MMP2 Homo sapiens 4313 2342 14
29 checkpoint kinase 1 CHK1_HUMAN CHEK1 Homo sapiens 1111 648 13
30 mitogen-activated protein kinase 14 MK14_HUMAN MAPK14 Homo sapiens 1432 3132 13
31 CD4 molecule CD4_HUMAN CD4 Homo sapiens 920 2744 13
32 mitogen-activated protein kinase 8 MK08_HUMAN MAPK8 Homo sapiens 5599 2863 12
33 prominin 1 PROM1_HUMAN PROM1 Homo sapiens 8842 522 12
34 ATR serine/threonine kinase ATR_HUMAN ATR Homo sapiens 545 866 12
35 SRY-box transcription factor 2 SOX2_HUMAN SOX2 Homo sapiens 6657 422 12
36 gap junction protein alpha 1 CXA1_HUMAN GJA1 Homo sapiens 2697 657 12
37 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 11
38 RAD51 recombinase RAD51_HUMAN RAD51 Homo sapiens 5888 537 11
39 H3 histone pseudogene 16 - H3P16 Homo sapiens 644914 2095 10
40 mutS homolog 2 MSH2_HUMAN MSH2 Homo sapiens 4436 199 9
41 prostaglandin D2 receptor PD2R_HUMAN PTGDR Homo sapiens 5729 491 9
42 H2A.X variant histone H2AX_HUMAN H2AX Homo sapiens 3014 412 9
43 MET proto-oncogene, receptor tyrosine kinase MET_HUMAN MET Homo sapiens 4233 791 9
44 GLI family zinc finger 1 GLI1_HUMAN GLI1 Homo sapiens 2735 334 9
45 enhancer of zeste 2 polycomb repressive complex 2 subunit EZH2_HUMAN EZH2 Homo sapiens 2146 470 9
46 prolactin PRL_HUMAN PRL Homo sapiens 5617 1285 9
47 B-Raf proto-oncogene, serine/threonine kinase BRAF_HUMAN BRAF Homo sapiens 673 872 9
48 sonic hedgehog signaling molecule SHH_HUMAN SHH Homo sapiens 6469 354 9
49 thymoma viral proto-oncogene 1 AKT1_MOUSE Akt1 Mus musculus 11651 3034 8
50 cyclin dependent kinase 1 CDK1_HUMAN CDK1 Homo sapiens 983 1023 8