Temozolomide

ATM serine/threonine kinase ; Homo sapiens







17 Article(s)
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1 35274103 XAF1 directs glioma response to temozolomide through apoptotic transition of autophagy by activation of ATM-AMPK signaling. 2022 Jan-Dec 1
2 35301087 PIMREG expression level predicts glioblastoma patient survival and affects temozolomide resistance and DNA damage response. 2022 Jun 1 1
3 35422863 The PARP1 Inhibitor Niraparib Represses DNA Damage Repair and Synergizes with Temozolomide for Antimyeloma Effects. 2022 1
4 35440003 Integrative analysis of therapy resistance and transcriptomic profiling data in glioblastoma cells identifies sensitization vulnerabilities for combined modality radiochemotherapy. 2022 Apr 19 2
5 33070553 Mutant IDH1 Enhances Temozolomide Sensitivity via Regulation of the ATM/CHK2 Pathway in Glioma. 2021 Apr 1
6 30796178 The SIAH1-HIPK2-p53ser46 Damage Response Pathway is Involved in Temozolomide-Induced Glioblastoma Cell Death. 2019 May 1
7 29378238 Loss of ATRX suppresses ATM dependent DNA damage repair by modulating H3K9me3 to enhance temozolomide sensitivity in glioma. 2018 Apr 10 1
8 28830922 Deletion of 11q in Neuroblastomas Drives Sensitivity to PARP Inhibition. 2017 Nov 15 2
9 25646660 MutL homolog 1 contributes to temozolomide-induced autophagy via ataxia-telangiectasia mutated in glioma. 2015 Jun 3
10 24737504 Temozolomide induces autophagy via ATM‑AMPK‑ULK1 pathways in glioma. 2014 Jul 2
11 23960094 Contribution of ATM and ATR to the resistance of glioblastoma and malignant melanoma cells to the methylating anticancer drug temozolomide. 2013 Nov 3
12 22768182 Human monocytes undergo excessive apoptosis following temozolomide activating the ATM/ATR pathway while dendritic cells and macrophages are resistant. 2012 2
13 23054561 ATM inhibitor KU-55933 increases the TMZ responsiveness of only inherently TMZ sensitive GBM cells. 2012 Dec 8
14 20540768 Quercetin abrogates chemoresistance in melanoma cells by modulating deltaNp73. 2010 Jun 11 2
15 19931733 Cytotoxic effects of temozolomide and radiation are additive- and schedule-dependent. 2009 Dec 1 5
16 18413665 AKT is activated in an ataxia-telangiectasia and Rad3-related-dependent manner in response to temozolomide and confers protection against drug-induced cell growth inhibition. 2008 Jul 1
17 15322239 DNA damage induced by temozolomide signals to both ATM and ATR: role of the mismatch repair system. 2004 Sep 2