Protein Name prostaglandin D2 receptor
Organism Homo sapiens
Gene ID 5729
Gene Symbol

PTGDR

UniProt Q13258 (PD2R_HUMAN)
Relationships Total Number of functionally related compound(s) : 491
Total Number of Articles : 648
Description

prostaglandin D2 receptor

Gene Summary

This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein is reported to be a receptor for prostaglandin D2, which is a mediator of allergic inflammation and allergic airway inflammation in asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

synonyms
  • prostaglandin D2 receptor
  • PGD2 receptor
  • AS1
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Properties