Protein Name enhancer of zeste 2 polycomb repressive complex 2 subunit
Organism Homo sapiens
Gene ID 2146
Gene Symbol

EZH2

UniProt Q15910 (EZH2_HUMAN), S4S3R8 (S4S3R8_HUMAN), A0A090N8E9 (A0A090N8E9_HUMAN)
Relationships Total Number of functionally related compound(s) : 470
Total Number of Articles : 1113
Description

enhancer of zeste 2 polycomb repressive complex 2 subunit

Gene Summary

This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]

synonyms
  • histone-lysine N-methyltransferase EZH2
  • enhancer of zeste homolog 2
  • lysine N-methyltransferase 6
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Properties