osimertinib


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235 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 727
2 epidermal growth factor receptor EGFR_MOUSE Egfr Mus musculus 13649 981 31
3 SAFB like transcription modulator SLTM_HUMAN SLTM Homo sapiens 79811 394 26
4 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 15
5 CD274 molecule PD1L1_HUMAN CD274 Homo sapiens 29126 1115 13
6 B-Raf proto-oncogene, serine/threonine kinase BRAF_HUMAN BRAF Homo sapiens 673 872 13
7 mitogen-activated protein kinase kinase 7 MP2K7_HUMAN MAP2K7 Homo sapiens 5609 1407 11
8 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 11
9 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 11
10 ALK receptor tyrosine kinase ALK_HUMAN ALK Homo sapiens 238 603 9
11 KRAS proto-oncogene, GTPase RASK_HUMAN KRAS Homo sapiens 3845 1547 9
12 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 8
13 ret proto-oncogene RET_HUMAN RET Homo sapiens 5979 674 8
14 erb-b2 receptor tyrosine kinase 2 ERBB2_HUMAN ERBB2 Homo sapiens 2064 2723 8
15 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha PK3CA_HUMAN PIK3CA Homo sapiens 5290 683 5
16 insulin like growth factor 1 receptor IGF1R_HUMAN IGF1R Homo sapiens 3480 814 5
17 proprotein convertase subtilisin/kexin type 9 PCSK9_HUMAN PCSK9 Homo sapiens 255738 518 5
18 BCL2 like 11 B2L11_HUMAN BCL2L11 Homo sapiens 10018 399 5
19 TXK tyrosine kinase TXK_HUMAN TXK Homo sapiens 7294 195 4
20 MET proto-oncogene, receptor tyrosine kinase MET_HUMAN MET Homo sapiens 4233 791 4
21 proprotein convertase subtilisin/kexin type 9 PCSK9_MOUSE Pcsk9 Mus musculus 100102 132 4
22 MCL1 apoptosis regulator, BCL2 family member MCL1_HUMAN MCL1 Homo sapiens 4170 1015 4
23 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 4
24 SRC proto-oncogene, non-receptor tyrosine kinase SRC_HUMAN SRC Homo sapiens 6714 2142 4
25 epidermal growth factor EGF_HUMAN EGF Homo sapiens 1950 1636 4
26 Moloney sarcoma oncogene MOS_MOUSE Mos Mus musculus 17451 147 3
27 erb-b2 receptor tyrosine kinase 3 ERBB3_HUMAN ERBB3 Homo sapiens 2065 299 3
28 fibroblast growth factor receptor 1 FGFR1_HUMAN FGFR1 Homo sapiens 2260 405 3
29 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 3
30 cyclin dependent kinase 4 CDK4_HUMAN CDK4 Homo sapiens 1019 868 3
31 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 3
32 cadherin 1 CADH1_HUMAN CDH1 Homo sapiens 999 1360 3
33 protein tyrosine kinase 2 beta FAK2_HUMAN PTK2B Homo sapiens 2185 848 3
34 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 3
35 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 3
36 transforming growth factor alpha TGFA_HUMAN TGFA Homo sapiens 7039 974 3
37 epidermal growth factor receptor Q9QX70_RAT Egfr Rattus norvegicus 24329 495 3
38 EPH receptor B2 EPHB2_HUMAN EPHB2 Homo sapiens 2048 321 3
39 sequestosome 1 SQSTM_HUMAN SQSTM1 Homo sapiens 8878 373 2
40 Yes1 associated transcriptional regulator YAP1_HUMAN YAP1 Homo sapiens 10413 666 2
41 neurotrophic receptor tyrosine kinase 1 NTRK1_HUMAN NTRK1 Homo sapiens 4914 401 2
42 BCL2-like 11 (apoptosis facilitator) B2L11_MOUSE Bcl2l11 Mus musculus 12125 103 2
43 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 2
44 musashi RNA binding protein 2 MSI2H_HUMAN MSI2 Homo sapiens 124540 41 2
45 EMAP like 4 EMAL4_HUMAN EML4 Homo sapiens 27436 62 2
46 transforming acidic coiled-coil containing protein 3 TACC3_HUMAN TACC3 Homo sapiens 10460 39 2
47 TNF receptor superfamily member 10a TR10A_HUMAN TNFRSF10A Homo sapiens 8797 237 2
48 platelet derived growth factor receptor beta PGFRB_HUMAN PDGFRB Homo sapiens 5159 417 2
49 signal transducer and activator of transcription 5A STA5A_HUMAN STAT5A Homo sapiens 6776 575 2
50 estrogen receptor 1 ESR1_HUMAN ESR1 Homo sapiens 2099 3003 2