osimertinib

AKT serine/threonine kinase 1 ; Homo sapiens







15 Article(s)
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1 35287683 Potential benefit of osismertinib plus bevacizumab in leptomeningeal metastasis with EGFR mutant non-small-cell lung cancer. 2022 Mar 14 1
2 33621951 MET inhibitor, capmatinib overcomes osimertinib resistance via suppression of MET/Akt/snail signaling in non-small cell lung cancer and decreased generation of cancer-associated fibroblasts. 2021 Feb 17 2
3 33724860 Thermal treatment decreases resistance to osimertinib in non-small cell lung cancer through the EGFR/PI3K/AKT pathway. 2021 May 1
4 33812963 Polyphyllin I reverses the resistance of osimertinib in non-small cell lung cancer cell through regulation of PI3K/Akt signaling. 2021 May 15 1
5 34077739 Osimertinib-resistant NSCLC cells activate ERBB2 and YAP/TAZ and are killed by neratinib. 2021 Aug 1
6 34242789 Acquired Resistance to Third-Generation EGFR Tyrosine Kinase Inhibitors in Patients With De Novo EGFRT790M-Mutant NSCLC. 2021 Nov 1
7 34267282 Combined FGFR and Akt pathway inhibition abrogates growth of FGFR1 overexpressing EGFR-TKI-resistant NSCLC cells. 2021 Jul 15 1
8 32256584 Pathological Mechanistic Studies of Osimertinib Resistance in Non-Small-Cell Lung Cancer Cells Using an Integrative Metabolomics-Proteomics Analysis. 2020 1
9 30145802 AZD9291 promotes autophagy and inhibits PI3K/Akt pathway in NSCLC cancer cells. 2019 Jan 5
10 30623574 Epithelial growth factor receptor tyrosine kinase inhibitors alleviate house dust mite allergen Der p2-induced IL-6 and IL-8. 2019 Apr 1
11 30993382 Overcoming acquired resistance of gefitinib in lung cancer cells without T790M by AZD9291 or Twist1 knockdown in vitro and in vivo. 2019 Jun 1
12 31446643 SHR-A1403, a novel c-mesenchymal-epithelial transition factor (c-Met) antibody-drug conjugate, overcomes AZD9291 resistance in non-small cell lung cancer cells overexpressing c-Met. 2019 Nov 2
13 31555510 Hsp90 inhibitors enhance the antitumoral effect of osimertinib in parental and osimertinib-resistant non-small cell lung cancer cell lines. 2019 Aug 1
14 29332537 AZD9291 Increases Sensitivity to Radiation in PC-9-IR Cells by Delaying DNA Damage Repair after Irradiation and Inducing Apoptosis. 2018 Mar 1
15 29797219 Loss of EGFR confers acquired resistance to AZD9291 in an EGFR-mutant non-small cell lung cancer cell line with an epithelial-mesenchymal transition phenotype. 2018 Aug 1