| Protein Name | Yes1 associated transcriptional regulator |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 10413 |
| Gene Symbol | YAP1 |
| UniProt | P46937 (YAP1_HUMAN), A0A024R3E4 (A0A024R3E4_HUMAN), K0KVU2 (K0KVU2_HUMAN), Q86T74 (Q86T74_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
666
Total Number of Articles : 1056 |
Description |
Yes1 associated transcriptional regulator |
| Gene Summary |
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013] |
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