Protein Name transforming growth factor alpha
Organism Homo sapiens
Gene ID 7039
Gene Symbol

TGFA

UniProt P01135 (TGFA_HUMAN), E7EPT6 (E7EPT6_HUMAN), F8VNR3 (F8VNR3_HUMAN)
Relationships Total Number of functionally related compound(s) : 974
Total Number of Articles : 1563
Description

transforming growth factor alpha

Gene Summary

This gene encodes a growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. This gene has been associated with many types of cancers, and it may also be involved in some cases of cleft lip/palate. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

synonyms
  • protransforming growth factor alpha
  • TGF-alpha
  • TFGA
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Properties