Protein Name | transforming growth factor alpha |
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Organism | Homo sapiens |
Gene ID | 7039 |
Gene Symbol | TGFA |
UniProt | P01135 (TGFA_HUMAN), E7EPT6 (E7EPT6_HUMAN), F8VNR3 (F8VNR3_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
974
Total Number of Articles : 1563 |
Description |
transforming growth factor alpha |
Gene Summary |
This gene encodes a growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. This gene has been associated with many types of cancers, and it may also be involved in some cases of cleft lip/palate. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] |
synonyms |
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Properties | |