Crizotinib


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342 Functionally related protein(s)
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Protein Name
UniProt Entry
Gene Symbol
Organism
NCBI Gene ID
# All related compound(s)
#Article(s)
1 ALK receptor tyrosine kinase ALK_HUMAN ALK Homo sapiens 238 603 1197
2 ROS proto-oncogene 1, receptor tyrosine kinase ROS1_HUMAN ROS1 Homo sapiens 6098 101 268
3 EMAP like 4 EMAL4_HUMAN EML4 Homo sapiens 27436 62 144
4 MET proto-oncogene, receptor tyrosine kinase MET_HUMAN MET Homo sapiens 4233 791 99
5 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 78
6 SAFB like transcription modulator SLTM_HUMAN SLTM Homo sapiens 79811 394 78
7 anaplastic lymphoma kinase ALK_MOUSE Alk Mus musculus 11682 127 38
8 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 22
9 hepatocyte growth factor HGF_HUMAN HGF Homo sapiens 3082 1036 19
10 CD74 molecule HG2A_HUMAN CD74 Homo sapiens 972 80 18
11 met proto-oncogene F8VQL0_MOUSE Met Mus musculus 17295 190 14
12 KRAS proto-oncogene, GTPase RASK_HUMAN KRAS Homo sapiens 3845 1547 12
13 Ros1 proto-oncogene ROS1_MOUSE Ros1 Mus musculus 19886 18 11
14 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 10
15 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 9
16 B-Raf proto-oncogene, serine/threonine kinase BRAF_HUMAN BRAF Homo sapiens 673 872 9
17 CD274 molecule PD1L1_HUMAN CD274 Homo sapiens 29126 1115 9
18 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 9
19 nudix hydrolase 1 8ODP_HUMAN NUDT1 Homo sapiens 4521 221 8
20 nucleophosmin 1 NPM_HUMAN NPM1 Homo sapiens 4869 371 8
21 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 8
22 ALK receptor tyrosine kinase - Alk Rattus norvegicus 266802 28 7
23 ret proto-oncogene RET_HUMAN RET Homo sapiens 5979 674 7
24 BH3 interacting domain death agonist BID_HUMAN BID Homo sapiens 637 1130 7
25 neurotrophic receptor tyrosine kinase 1 NTRK1_HUMAN NTRK1 Homo sapiens 4914 401 7
26 insulin like growth factor 1 receptor IGF1R_HUMAN IGF1R Homo sapiens 3480 814 7
27 glutamic--pyruvic transaminase ALAT1_HUMAN GPT Homo sapiens 2875 774 6
28 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 6
29 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 6
30 MYC proto-oncogene, bHLH transcription factor MYC_HUMAN MYC Homo sapiens 4609 2261 6
31 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 6
32 erb-b2 receptor tyrosine kinase 2 ERBB2_HUMAN ERBB2 Homo sapiens 2064 2723 5
33 heat shock protein 90 alpha family class A member 1 HS90A_HUMAN HSP90AA1 Homo sapiens 3320 1552 5
34 hepatocyte growth factor HGF_MOUSE Hgf Mus musculus 15234 356 5
35 RAN binding protein 2 RBP2_HUMAN RANBP2 Homo sapiens 5903 43 5
36 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 5
37 macrophage stimulating 1 receptor RON_HUMAN MST1R Homo sapiens 4486 86 5
38 thymoma viral proto-oncogene 1 AKT1_MOUSE Akt1 Mus musculus 11651 3034 4
39 solute carrier family 34 member 2 NPT2B_HUMAN SLC34A2 Homo sapiens 10568 31 4
40 AXL receptor tyrosine kinase UFO_HUMAN AXL Homo sapiens 558 302 4
41 golgi associated PDZ and coiled-coil motif containing GOPC_HUMAN GOPC Homo sapiens 57120 27 4
42 echinoderm microtubule associated protein like 4 EMAL4_MOUSE Eml4 Mus musculus 78798 11 4
43 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha PK3CA_HUMAN PIK3CA Homo sapiens 5290 683 4
44 Anaplastic lymphoma kinase Q7KJ08_DROME Alk Drosophila melanogaster 53425 16 3
45 kinesin family member 5B KINH_HUMAN KIF5B Homo sapiens 3799 59 3
46 twist family bHLH transcription factor 1 TWST1_HUMAN TWIST1 Homo sapiens 7291 370 3
47 ABL proto-oncogene 1, non-receptor tyrosine kinase ABL1_HUMAN ABL1 Homo sapiens 25 989 3
48 lamin A/C LMNA_HUMAN LMNA Homo sapiens 4000 356 3
49 ATP-binding cassette, sub-family B (MDR/TAP), member 1B MDR1B_MOUSE Abcb1b Mus musculus 18669 469 3
50 insulin like growth factor 1 IGF1_HUMAN IGF1 Homo sapiens 3479 1917 3