Crizotinib

BCL2 apoptosis regulator ; Homo sapiens







6 Article(s)
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PMID
Title
Pub. Year
#Total Relationships
1 35155225 An Insight on the Pathways Involved in Crizotinib and Sunitinib Induced Hepatotoxicity in HepG2 Cells and Animal Model. 2022 1
2 33597889 Crizotinib and Sunitinib Induce Hepatotoxicity and Mitochondrial Apoptosis in L02 Cells via ROS and Nrf2 Signaling Pathway. 2021 1
3 32484926 Elimination of dormant, autophagic ovarian cancer cells and xenografts through enhanced sensitivity to anaplastic lymphoma kinase inhibition. 2020 Aug 1 2
4 30679328 Blockade of crizotinib-induced BCL2 elevation in ALK-positive anaplastic large cell lymphoma triggers autophagy associated with cell death. 2019 Jul 2
5 29743557 Inhibition of Bcl-2/Bcl-xL and c-MET causes synthetic lethality in model systems of glioblastoma. 2018 May 9 1
6 24486291 Crizotinib (PF-2341066) induces apoptosis due to downregulation of pSTAT3 and BCL-2 family proteins in NPM-ALK(+) anaplastic large cell lymphoma. 2014 Apr 1