Crizotinib

nudix hydrolase 1 ; Homo sapiens







8 Article(s)
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Pub. Year
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1 30692572 Differential anti-tumour effects of MTH1 inhibitors in patient-derived 3D colorectal cancer cultures. 2019 Jan 28 1
2 29420337 Anticancer effect of (S)-crizotinib on osteosarcoma cells by targeting MTH1 and activating reactive oxygen species. 2018 Apr 5
3 30024628 HMTH1 induces the metastasis and recurrence of the parotid adenoma by repairing DNA damage. 2018 Jul 2
4 28882182 (S)-crizotinib induces apoptosis in human non-small cell lung cancer cells by activating ROS independent of MTH1. 2017 Sep 7 4
5 26764587 Directly Binding Rather than Induced-Fit Dominated Binding Affinity Difference in (S)- and (R)-Crizotinib Bound MTH1. 2016 Feb 9 5
6 26298289 AuNP flares-capped mesoporous silica nanoplatform for MTH1 detection and inhibition. 2015 Nov 1
7 26677850 Influence of Chirality of Crizotinib on Its MTH1 Protein Inhibitory Activity: Insight from Molecular Dynamics Simulations and Binding Free Energy Calculations. 2015 9
8 24695225 Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy. 2014 Apr 10 3