Protein Name met proto-oncogene
Organism Mus musculus
Gene ID 17295
Gene Symbol

Met

UniProt F8VQL0 (F8VQL0_MOUSE), A4FUV6 (A4FUV6_MOUSE)
Relationships Total Number of functionally related compound(s) : 190
Total Number of Articles : 226
Description

met proto-oncogene

Gene Summary

Enables hepatocyte growth factor receptor activity. Involved in cell surface receptor signaling pathway; modulation of chemical synaptic transmission; and positive chemotaxis. Acts upstream of or within several processes, including hepatocyte growth factor receptor signaling pathway; regulation of cytokine production; and striated muscle cell differentiation. Located in membrane. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; genitourinary system; and limb. Used to study Gilles de la Tourette syndrome; autism spectrum disorder; breast cancer; and gestational diabetes. Human ortholog(s) of this gene implicated in autistic disorder; autosomal recessive nonsyndromic deafness 97; carcinoma (multiple); distal arthrogryposis; and multiple myeloma. Orthologous to human MET (MET proto-oncogene, receptor tyrosine kinase). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • hepatocyte growth factor receptor
  • HGF receptor
  • HGF/SF receptor
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Properties