Crizotinib

signal transducer and activator of transcription 3 ; Homo sapiens







9 Article(s)
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1 34657149 Tyrosine phosphatases regulate resistance to ALK inhibitors in ALK+ anaplastic large cell lymphoma. 2022 Feb 3 1
2 33887553 Downregulation of PDGFRß Signaling Overcomes Crizotinib Resistance in a TYRO3 and ALK Mutated Neuroendocrine-Like Tumor. 2021 Jul 1
3 32111984 SOX13 promotes colorectal cancer metastasis by transactivating SNAI2 and c-MET. 2020 Apr 3
4 32484926 Elimination of dormant, autophagic ovarian cancer cells and xenografts through enhanced sensitivity to anaplastic lymphoma kinase inhibition. 2020 Aug 1 2
5 29444468 A major component of vitamin E, α-tocopherol inhibits the anti-tumor activity of crizotinib against cells transformed by EML4-ALK. 2018 Apr 15 1
6 29755689 A subgroup of pleural mesothelioma expresses ALK protein and may be targetable by combined rapamycin and crizotinib therapy. 2018 Apr 17 1
7 27753543 STAT3-targeted treatment with silibinin overcomes the acquired resistance to crizotinib in ALK-rearranged lung cancer. 2016 Dec 16 3
8 26384345 Crizotinib induces autophagy through inhibition of the STAT3 pathway in multiple lung cancer cell lines. 2015 Nov 24 5
9 24486291 Crizotinib (PF-2341066) induces apoptosis due to downregulation of pSTAT3 and BCL-2 family proteins in NPM-ALK(+) anaplastic large cell lymphoma. 2014 Apr 1