SB 203580


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1662 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 mitogen-activated protein kinase 14 MK14_HUMAN MAPK14 Homo sapiens 1432 3132 1669
2 mitogen-activated protein kinase 14 MK14_MOUSE Mapk14 Mus musculus 26416 2012 783
3 mitogen activated protein kinase 14 Q56A33_RAT Mapk14 Rattus norvegicus 81649 1429 677
4 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 496
5 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 193
6 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 152
7 C-X-C motif chemokine ligand 8 IL8_HUMAN CXCL8 Homo sapiens 3576 4038 123
8 mitogen-activated protein kinase 8 MK08_HUMAN MAPK8 Homo sapiens 5599 2863 117
9 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 107
10 interleukin 1 beta IL1B_HUMAN IL1B Homo sapiens 3553 3575 92
11 transforming growth factor beta 1 TGFB1_HUMAN TGFB1 Homo sapiens 7040 2953 78
12 tumor necrosis factor TNFA_RAT Tnf Rattus norvegicus 24835 3922 77
13 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 74
14 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 64
15 mitogen activated protein kinase 3 MK03_RAT Mapk3 Rattus norvegicus 50689 1665 59
16 tumor necrosis factor TNFA_MOUSE Tnf Mus musculus 21926 5931 58
17 heat shock protein family B (small) member 1 HSPB1_HUMAN HSPB1 Homo sapiens 3315 556 55
18 matrix metallopeptidase 9 MMP9_HUMAN MMP9 Homo sapiens 4318 2470 54
19 prostaglandin-endoperoxide synthase 2 PGH2_HUMAN PTGS2 Homo sapiens 5743 2572 49
20 mitogen-activated protein kinase 1 MK01_MOUSE Mapk1 Mus musculus 26413 1992 49
21 matrix metallopeptidase 2 MMP2_HUMAN MMP2 Homo sapiens 4313 2342 48
22 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 48
23 interleukin 1 beta Q5BKB0_RAT Il1b Rattus norvegicus 24494 2252 48
24 MAPK activated protein kinase 2 MAPK2_HUMAN MAPKAPK2 Homo sapiens 9261 229 37
25 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 37
26 interleukin 6 IL6_MOUSE Il6 Mus musculus 16193 3985 36
27 mitogen-activated protein kinase 14 A6QLR9_BOVIN MAPK14 Bos taurus 534492 100 35
28 matrix metallopeptidase 1 MMP1_HUMAN MMP1 Homo sapiens 4312 1304 32
29 mitochondrially encoded cytochrome c oxidase II COX2_HUMAN COX2 Homo sapiens 4513 5330 31
30 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 NFKB1_MOUSE Nfkb1 Mus musculus 18033 3161 31
31 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 31
32 C-C motif chemokine ligand 2 CCL2_HUMAN CCL2 Homo sapiens 6347 1858 30
33 interleukin 1 alpha IL1A_HUMAN IL1A Homo sapiens 3552 2741 29
34 mitogen-activated protein kinase 11 MK11_HUMAN MAPK11 Homo sapiens 5600 69 27
35 interferon gamma IFNG_HUMAN IFNG Homo sapiens 3458 3371 27
36 caspase 3 CASP3_RAT Casp3 Rattus norvegicus 25402 2178 27
37 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 27
38 mitogen-activated protein kinase 8 MK08_MOUSE Mapk8 Mus musculus 26419 1537 27
39 mitogen-activated protein kinase 3 MK03_MOUSE Mapk3 Mus musculus 26417 1527 26
40 mitogen-activated protein kinase 8 MK08_RAT Mapk8 Rattus norvegicus 116554 1068 26
41 interleukin 10 IL10_HUMAN IL10 Homo sapiens 3586 2075 24
42 nitric oxide synthase 2, inducible NOS2_MOUSE Nos2 Mus musculus 18126 2585 24
43 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 24
44 angiotensinogen ANGT_RAT Agt Rattus norvegicus 24179 2598 24
45 RELA proto-oncogene, NF-kB subunit TF65_HUMAN RELA Homo sapiens 5970 1514 24
46 nitric oxide synthase 2 NOS2_RAT Nos2 Rattus norvegicus 24599 1861 23
47 insulin INS_HUMAN INS Homo sapiens 3630 7950 23
48 toll-like receptor 4 TLR4_MOUSE Tlr4 Mus musculus 21898 2266 23
49 Jun proto-oncogene, AP-1 transcription factor subunit JUN_HUMAN JUN Homo sapiens 3725 1260 23
50 heme oxygenase 1 HMOX1_HUMAN HMOX1 Homo sapiens 3162 1764 23