SB 203580

matrix metallopeptidase 2 ; Homo sapiens







48 Article(s)
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Pub. Year
#Total Relationships
1 34015597 Targeting TSP-1 decreased periodontitis by attenuating extracellular matrix degradation and alveolar bone destruction. 2021 Jul 1
2 34572296 Ailanthoidol, a Neolignan, Suppresses TGF-β1-Induced HepG2 Hepatoblastoma Cell Progression. 2021 Aug 30 1
3 32224968 Luteolin-7-O-Glucoside Inhibits Oral Cancer Cell Migration and Invasion by Regulating Matrix Metalloproteinase-2 Expression and Extracellular Signal-Regulated Kinase Pathway. 2020 Mar 26 1
4 30889629 Sea cucumber extract TBL-12 inhibits the proliferation, migration, and invasion of human prostate cancer cells through the p38 mitogen-activated protein kinase and intrinsic caspase apoptosis pathway. 2019 Jun 1
5 31920328 TMEFF2 inhibits pancreatic cancer cells proliferation, migration, and invasion by suppressing phosphorylation of the MAPK signaling pathway. 2019 1
6 29344204 Silibinin inhibits the migration and invasion of human gastric cancer SGC7901 cells by downregulating MMP-2 and MMP-9 expression via the p38MAPK signaling pathway. 2017 Dec 2
7 26179980 Effects of urban particulate matter with high glucose on human monocytes U937. 2016 Apr 1
8 26474590 Naringin inhibits the invasion and migration of human glioblastoma cell via downregulation of MMP-2 and MMP-9 expression and inactivation of p38 signaling pathway. 2016 Mar 1
9 27035160 Salinomycin causes migration and invasion of human fibrosarcoma cells by inducing MMP-2 expression via PI3-kinase, ERK-1/2 and p38 kinase pathways. 2016 Jun 1
10 27082056 Ampelopsin suppresses TNF-α-induced migration and invasion of U2OS osteosarcoma cells. 2016 Jun 1
11 27441000 Fasudil inhibits LPS-induced migration of retinal microglial cells via regulating p38-MAPK signaling pathway. 2016 1
12 25502212 Baicalein inhibits the invasion of gastric cancer cells by suppressing the activity of the p38 signaling pathway. 2015 Feb 1
13 25811965 Baicalein inhibits MMP-2 expression in human ovarian cancer cells by suppressing the p38 MAPK-dependent NF-κB signaling pathway. 2015 Jul 1
14 26497050 Chloride intracellular channel 1 regulates migration and invasion in gastric cancer by triggering the ROS-mediated p38 MAPK signaling pathway. 2015 Dec 1
15 24587321 Baicalein reduces the invasion of glioma cells via reducing the activity of p38 signaling pathway. 2014 1
16 24841706 Resveratrol attenuates matrix metalloproteinase-9 and -2-regulated differentiation of HTB94 chondrosarcoma cells through the p38 kinase and JNK pathways. 2014 Jul 1
17 25011999 Enamel matrix derivative protein enhances production of matrixmetalloproteinase-2 by osteoblasts. 2014 Jul 10 1
18 25195681 Curcumin inhibits the proliferation and invasiveness of MHCC97-H cells via p38 signaling pathway. 2014 Nov 1
19 25242117 Overexpression of syntenin enhances hepatoma cell proliferation and invasion: potential roles in human hepatoma. 2014 Dec 2
20 25244643 Effect of IL-17A on the migration and invasion of NPC cells and related mechanisms. 2014 1
21 25250801 IL-17A promotes the migration and invasiveness of cervical cancer cells by coordinately activating MMPs expression via the p38/NF-κB signal pathway. 2014 1
22 25348737 Matrine reduces the proliferation and invasion of colorectal cancer cells via reducing the activity of p38 signaling pathway. 2014 Dec 1
23 23387975 Baicalin suppresses migration, invasion and metastasis of breast cancer via p38MAPK signaling pathway. 2013 Jul 1 2
24 23456298 S100A8 and S100A9 promotes invasion and migration through p38 mitogen-activated protein kinase-dependent NF-κB activation in gastric cancer cells. 2013 Mar 2
25 23707804 Brazilein suppresses migration and invasion of MDA-MB-231 breast cancer cells. 2013 Jul 5 1
26 23950935 Mechanical stretch increases MMP-2 production in vascular smooth muscle cells via activation of PDGFR-β/Akt signaling pathway. 2013 1
27 24030463 Delta-opioid receptors attenuate TNF-α-induced MMP-2 secretion from human ONH astrocytes. 2013 Oct 9 1
28 22684547 Sphingosine kinase 1 enhances colon cancer cell proliferation and invasion by upregulating the production of MMP-2/9 and uPA via MAPK pathways. 2012 Dec 1
29 22695858 Suppressive effects of electrochemically reduced water on matrix metalloproteinase-2 activities and in vitro invasion of human fibrosarcoma HT1080 cells. 2012 May 2
30 21210297 Acacetin inhibits the invasion and migration of human non-small cell lung cancer A549 cells by suppressing the p38α MAPK signaling pathway. 2011 Apr 1
31 21468925 Attenuated expression and function of the RECK tumor suppressor under hypoxic conditions is mediated by the MAPK signaling pathways. 2011 Jan 1
32 21574189 Silibinin inhibits the invasion and migration of renal carcinoma 786-O cells in vitro, inhibits the growth of xenografts in vivo and enhances chemosensitivity to 5-fluorouracil and paclitaxel. 2011 Oct 1
33 19693651 Acacetin, a flavonoid, inhibits the invasion and migration of human prostate cancer DU145 cells via inactivation of the p38 MAPK signaling pathway. 2010 Jan 1
34 20607722 Down-regulation of MMP-2 through the p38 MAPK-NF-kappaB-dependent pathway by aloe-emodin leads to inhibition of nasopharyngeal carcinoma cell invasion. 2010 Sep 3
35 20688742 Downregulation of matrix metalloproteinase-2 in corneal fibroblasts by interleukin-1 receptor antagonist released from corneal epithelial cells. 2010 Dec 1
36 19590887 Mechanical force enhances MMP-2 activation via p38 signaling pathway in human retinal pigment epithelial cells. 2009 Nov 3
37 16407830 MAPKAPK2 and HSP27 are downstream effectors of p38 MAP kinase-mediated matrix metalloproteinase type 2 activation and cell invasion in human prostate cancer. 2006 May 18 2
38 16600109 [p38/ERK signal pathways regulating the expression of type I collagen and activity of MMP-2 in TGF-beta1-stimulated HLF-02 cells]. 2006 Feb 2
39 15833883 Genistein inhibits p38 map kinase activation, matrix metalloproteinase type 2, and cell invasion in human prostate epithelial cells. 2005 Apr 15 1
40 16000878 Tetraspanin CD9 induces MMP-2 expression by activating p38 MAPK, JNK and c-Jun pathways in human melanoma cells. 2005 Jun 30 1
41 14742313 Proanthocyanidins from grape seeds inhibit expression of matrix metalloproteinases in human prostate carcinoma cells, which is associated with the inhibition of activation of MAPK and NF kappa B. 2004 Jun 1
42 15102045 Examination of the signal transduction pathways leading to activation of gelatinolytic activity by interleukin-1alpha and Porphyromonas gingivalis in human osteosarcoma cells. 2004 Jun 1
43 15272234 Interleukin-1beta stimulates matrix metalloproteinase-2 expression via a prostaglandin E2-dependent mechanism in human chondrocytes. 2004 Jun 30 1
44 14559821 SH2 domain containing protein tyrosine phosphatase 2 regulates concanavalin A-dependent secretion and activation of matrix metalloproteinase 2 via the extracellular signal-regulated kinase and p38 pathways. 2003 Oct 1 1
45 14598883 Growth factor-dependent activation of the MAPK pathway in human pancreatic cancer: MEK/ERK and p38 MAP kinase interaction in uPA synthesis. 2003 1
46 11918086 An inhibitor of stress-activated MAP-kinases reduces invasion and MMP-2 expression of malignant melanoma cells. 2002 1
47 12134900 Modulation of phorbol ester-induced regulation of matrix metalloproteinases and tissue inhibitors of metalloproteinases by SB203580, a specific inhibitor of p38 mitogen-activated protein kinase. 2002 Jul 6
48 12198653 Apoptosis of human hepatic myofibroblasts promotes activation of matrix metalloproteinase-2. 2002 Sep 1