osimertinib


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79 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 416
2 epidermal growth factor receptor EGFR_MOUSE Egfr Mus musculus 13649 981 12
3 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 6
4 ALK receptor tyrosine kinase ALK_HUMAN ALK Homo sapiens 238 603 6
5 AXL receptor tyrosine kinase UFO_HUMAN AXL Homo sapiens 558 302 4
6 CD274 molecule PD1L1_HUMAN CD274 Homo sapiens 29126 1115 4
7 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 4
8 erb-b2 receptor tyrosine kinase 2 ERBB2_HUMAN ERBB2 Homo sapiens 2064 2723 4
9 ret proto-oncogene RET_HUMAN RET Homo sapiens 5979 674 4
10 EPH receptor B2 EPHB2_HUMAN EPHB2 Homo sapiens 2048 321 3
11 epidermal growth factor EGF_HUMAN EGF Homo sapiens 1950 1636 3
12 ATP binding cassette subfamily G member 2 (Junior blood group) ABCG2_HUMAN ABCG2 Homo sapiens 9429 1370 3
13 BCL2 like 11 B2L11_HUMAN BCL2L11 Homo sapiens 10018 399 3
14 proprotein convertase subtilisin/kexin type 9 PCSK9_HUMAN PCSK9 Homo sapiens 255738 518 2
15 programmed cell death 1 PDCD1_HUMAN PDCD1 Homo sapiens 5133 637 2
16 smoothened, frizzled class receptor SMO_HUMAN SMO Homo sapiens 6608 291 2
17 B-Raf proto-oncogene, serine/threonine kinase BRAF_HUMAN BRAF Homo sapiens 673 872 2
18 forkhead box O3 FOXO3_HUMAN FOXO3 Homo sapiens 2309 544 2
19 protein tyrosine kinase 2 FAK1_HUMAN PTK2 Homo sapiens 5747 1151 2
20 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 2
21 integrin subunit beta 3 ITB3_HUMAN ITGB3 Homo sapiens 3690 272 1
22 thyroid peroxidase PERT_HUMAN TPO Homo sapiens 7173 510 1
23 Yes1 associated transcriptional regulator YAP1_HUMAN YAP1 Homo sapiens 10413 666 1
24 stearoyl-CoA desaturase SCD_HUMAN SCD Homo sapiens 6319 396 1
25 ATP-binding cassette, sub-family B (MDR/TAP), member 1A MDR1A_MOUSE Abcb1a Mus musculus 18671 272 1
26 protein tyrosine kinase 2 beta FAK2_HUMAN PTK2B Homo sapiens 2185 848 1
27 CASP8 and FADD like apoptosis regulator CFLAR_HUMAN CFLAR Homo sapiens 8837 339 1
28 CD44 molecule (Indian blood group) CD44_HUMAN CD44 Homo sapiens 960 1234 1
29 MCL1 apoptosis regulator, BCL2 family member MCL1_HUMAN MCL1 Homo sapiens 4170 1015 1
30 DEAD-box helicase 53 DDX53_HUMAN DDX53 Homo sapiens 168400 79 1
31 IL2 inducible T cell kinase ITK_HUMAN ITK Homo sapiens 3702 387 1
32 neurofibromin 1 NF1_HUMAN NF1 Homo sapiens 4763 413 1
33 histone deacetylase 3 HDAC3_HUMAN HDAC3 Homo sapiens 8841 245 1
34 endoplasmic reticulum to nucleus signaling 1 ERN1_HUMAN ERN1 Homo sapiens 2081 451 1
35 mitogen-activated protein kinase kinase kinase 8 M3K8_HUMAN MAP3K8 Homo sapiens 1326 92 1
36 YES proto-oncogene 1, Src family tyrosine kinase YES_HUMAN YES1 Homo sapiens 7525 46 1
37 aldehyde dehydrogenase family 1, subfamily A1 AL1A1_MOUSE Aldh1a1 Mus musculus 11668 113 1
38 oleoyl-ACP hydrolase SAST_HUMAN OLAH Homo sapiens 55301 24 1
39 mitogen-activated protein kinase kinase 7 MP2K7_HUMAN MAP2K7 Homo sapiens 5609 1407 1
40 eukaryotic translation initiation factor 2 alpha kinase 3 E2AK3_HUMAN EIF2AK3 Homo sapiens 9451 737 1
41 SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 TICN1_HUMAN SPOCK1 Homo sapiens 6695 21 1
42 CREB regulated transcription coactivator 2 CRTC2_MOUSE Crtc2 Mus musculus 74343 347 1
43 proprotein convertase subtilisin/kexin type 9 PCSK9_MOUSE Pcsk9 Mus musculus 100102 132 1
44 beclin 1 BECN1_HUMAN BECN1 Homo sapiens 8678 847 1
45 Janus kinase 2 JAK2_HUMAN JAK2 Homo sapiens 3717 1038 1
46 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha PK3CA_HUMAN PIK3CA Homo sapiens 5290 683 1
47 glycogen synthase kinase 3 beta GSK3B_HUMAN GSK3B Homo sapiens 2932 1189 1
48 microRNA 34a - MIR34A Homo sapiens 407040 350 1
49 erb-b2 receptor tyrosine kinase 3 ERBB3_HUMAN ERBB3 Homo sapiens 2065 299 1
50 epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) Q7SZF7_DANRE egfra Danio rerio 378478 19 1