CPRiL

Protein Name	ATP-binding cassette, sub-family B member 1A
Organism	Mus musculus
Gene ID	18671
Gene Symbol	Abcb1a
UniProt	P21447 (MDR1A_MOUSE)
Relationships	Total Number of functionally related compound(s) : 272 Total Number of Articles : 302
Description	ATP-binding cassette, sub-family B member 1A
Gene Summary	The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a p-glycoprotein which actively transports a variety of hydrophobic amphipathic drugs and plays a major role in the blood-brain barrier permeability of certain drugs. [provided by RefSeq, Jul 2008]
synonyms	ATP-dependent translocase ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1A ATP-binding cassette, sub-family B (MDR/TAP), member 4 ATP-binding cassette, subfamily B, member 1A P-glycoprotein 3 ecotropic viral integration site 32 multi-drug resistance 3 multidrug resistance protein 3 multiple drug resistant 1a phospholipid transporter ABCB1 Abcb4 Evi32 Mdr1a Mdr3 P-gp Pgp Pgy-3 Pgy3 mdr-3 Click to show/hide the synonyms
Properties