Protein Name protein tyrosine kinase 2
Organism Homo sapiens
Gene ID 5747
Gene Symbol


UniProt Q05397 (FAK1_HUMAN), Q658W2 (Q658W2_HUMAN), Q59GN8 (Q59GN8_HUMAN), Q59GM6 (Q59GM6_HUMAN)
Relationships Total Number of functionally related compound(s) : 1151
Total Number of Articles : 2075

protein tyrosine kinase 2

Gene Summary

This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2017]

  • focal adhesion kinase 1
  • FAK-related non-kinase polypeptide
  • PTK2 protein tyrosine kinase 2
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