| Protein Name | CASP8 and FADD like apoptosis regulator |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 8837 |
| Gene Symbol | CFLAR |
| UniProt | O15519 (CFLAR_HUMAN), A0A024R3Y4 (A0A024R3Y4_HUMAN), A0A024R3Y3 (A0A024R3Y3_HUMAN), A0A336TY74 (A0A336TY74_HUMAN), E9PAP3 (E9PAP3_HUMAN), Q59F61 (Q59F61_HUMAN), B4E361 (B4E361_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
339
Total Number of Articles : 445 |
Description |
CASP8 and FADD like apoptosis regulator |
| Gene Summary |
The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists. [provided by RefSeq, Feb 2011] |
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| Properties | |