Protein Name beclin 1
Organism Homo sapiens
Gene ID 8678
Gene Symbol


UniProt Q14457 (BECN1_HUMAN), A0A024R1X5 (A0A024R1X5_HUMAN), W0FFG4 (W0FFG4_HUMAN), E7EV84 (E7EV84_HUMAN), B4DQ36 (B4DQ36_HUMAN)
Relationships Total Number of functionally related compound(s) : 847
Total Number of Articles : 1372

beclin 1

Gene Summary

This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

  • beclin-1
  • ATG6 autophagy related 6 homolog
  • beclin 1 (coiled-coil, moesin-like BCL2-interacting protein)
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