| Protein Name | beclin 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 8678 |
| Gene Symbol | BECN1 |
| UniProt | Q14457 (BECN1_HUMAN), A0A024R1X5 (A0A024R1X5_HUMAN), W0FFG4 (W0FFG4_HUMAN), E7EV84 (E7EV84_HUMAN), B4DQ36 (B4DQ36_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
847
Total Number of Articles : 1372 |
Description |
beclin 1 |
| Gene Summary |
This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
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| Properties | |