Spironolactone


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538 Functionally related protein(s)
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Protein Name
UniProt Entry
Gene Symbol
Organism
NCBI Gene ID
# All related compound(s)
#Article(s)
1 nuclear receptor subfamily 3 group C member 2 MCR_HUMAN NR3C2 Homo sapiens 4306 261 176
2 nuclear receptor subfamily 3, group C, member 2 MCR_RAT Nr3c2 Rattus norvegicus 25672 199 86
3 renin RENI_HUMAN REN Homo sapiens 5972 1345 83
4 angiotensin I converting enzyme ACE_HUMAN ACE Homo sapiens 1636 1884 72
5 nuclear receptor subfamily 3, group C, member 2 A3KN90_MOUSE Nr3c2 Mus musculus 110784 103 31
6 angiotensinogen ANGT_HUMAN AGT Homo sapiens 183 2109 27
7 androgen receptor ANDR_HUMAN AR Homo sapiens 367 1832 19
8 transforming growth factor, beta 1 TGFB1_RAT Tgfb1 Rattus norvegicus 59086 1730 16
9 angiotensinogen ANGT_RAT Agt Rattus norvegicus 24179 2598 16
10 natriuretic peptide B ANFB_HUMAN NPPB Homo sapiens 4879 736 15
11 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 14
12 serpin family E member 1 PAI1_RAT Serpine1 Rattus norvegicus 24617 322 12
13 insulin INS_HUMAN INS Homo sapiens 3630 7950 11
14 serpin family E member 1 PAI1_HUMAN SERPINE1 Homo sapiens 5054 1182 10
15 angiotensin I converting enzyme ACE_RAT Ace Rattus norvegicus 24310 947 9
16 transforming growth factor beta 1 TGFB1_HUMAN TGFB1 Homo sapiens 7040 2953 8
17 proopiomelanocortin COLI_HUMAN POMC Homo sapiens 5443 2059 8
18 fibronectin 1 F1LST1_RAT Fn1 Rattus norvegicus 25661 654 8
19 tumor necrosis factor TNFA_RAT Tnf Rattus norvegicus 24835 3922 7
20 angiotensin converting enzyme 2 ACE2_HUMAN ACE2 Homo sapiens 59272 897 7
21 serum/glucocorticoid regulated kinase 1 Q68G05_RAT Sgk1 Rattus norvegicus 29517 85 7
22 mitogen activated protein kinase 3 MK03_RAT Mapk3 Rattus norvegicus 50689 1665 7
23 ERCC excision repair 3, TFIIH core complex helicase subunit ERCC3_HUMAN ERCC3 Homo sapiens 2071 36 7
24 renin RENI_RAT Ren Rattus norvegicus 24715 940 7
25 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 6
26 angiotensinogen (serpin peptidase inhibitor, clade A, member 8) Q3UTR7_MOUSE Agt Mus musculus 11606 860 6
27 interleukin 6 IL6_RAT Il6 Rattus norvegicus 24498 2269 6
28 kallikrein related peptidase 4 KLK4_HUMAN KLK4 Homo sapiens 9622 442 6
29 transmembrane serine protease 2 TMPS2_HUMAN TMPRSS2 Homo sapiens 7113 244 6
30 cellular communication network factor 2 CCN2_RAT Ccn2 Rattus norvegicus 64032 293 6
31 selenium binding protein 1 SBP1_HUMAN SELENBP1 Homo sapiens 8991 688 5
32 nuclear receptor subfamily 3 group C member 1 GCR_HUMAN NR3C1 Homo sapiens 2908 976 5
33 prolactin PRL_HUMAN PRL Homo sapiens 5617 1285 5
34 C-reactive protein CRP_HUMAN CRP Homo sapiens 1401 2285 5
35 C-C motif chemokine ligand 2 CCL2_HUMAN CCL2 Homo sapiens 6347 1858 5
36 mitogen activated protein kinase 14 Q56A33_RAT Mapk14 Rattus norvegicus 81649 1429 5
37 cytochrome P450 3A14 CP3AE_CAVPO Cyp3a14 Cavia porcellus 100379244 82 5
38 CD59 molecule (CD59 blood group) CD59_HUMAN CD59 Homo sapiens 966 1815 4
39 cytochrome P450 family 4 subfamily F member 3 CP4F3_HUMAN CYP4F3 Homo sapiens 4051 2473 4
40 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Q8R427_RAT Abcb1b Rattus norvegicus 24646 765 4
41 cytochrome P450, family 2, subfamily g, polypeptide 1 CP2G1_RAT Cyp2g1 Rattus norvegicus 25251 2275 4
42 hydroxysteroid 11-beta dehydrogenase 2 DHI2_HUMAN HSD11B2 Homo sapiens 3291 300 4
43 endothelin 1 EDN1_HUMAN EDN1 Homo sapiens 1906 1547 4
44 endothelin 1 EDN1_RAT Edn1 Rattus norvegicus 24323 1418 4
45 interferon gamma IFNG_HUMAN IFNG Homo sapiens 3458 3371 4
46 serum/glucocorticoid regulated kinase 1 SGK1_HUMAN SGK1 Homo sapiens 6446 232 4
47 progesterone receptor PRGR_HUMAN PGR Homo sapiens 5241 863 4
48 cytochrome P450, family 11, subfamily b, polypeptide 2 - Cyp11b2 Rattus norvegicus 24294 56 4
49 vascular endothelial growth factor A VEGFA_RAT Vegfa Rattus norvegicus 83785 1424 4
50 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 4