Protein Name kallikrein related peptidase 4
Organism Homo sapiens
Gene ID 9622
Gene Symbol

KLK4

UniProt Q9Y5K2 (KLK4_HUMAN), Q5BQA0 (Q5BQA0_HUMAN), A0A0C4DFQ5 (A0A0C4DFQ5_HUMAN), Q96PT1 (Q96PT1_HUMAN)
Relationships Total Number of functionally related compound(s) : 442
Total Number of Articles : 560
Description

kallikrein related peptidase 4

Gene Summary

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In some tissues its expression is hormonally regulated. The expression pattern of a similar mouse protein in murine developing teeth supports a role for the protein in the degradation of enamel proteins. Several transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Dec 2014]

synonyms
  • kallikrein-4
  • androgen-regulated message 1
  • enamel matrix serine protease 1
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Properties