Protein Name nuclear receptor subfamily 3, group C, member 2
Organism Rattus norvegicus
Gene ID 25672
Gene Symbol

Nr3c2

UniProt P22199 (MCR_RAT)
Relationships Total Number of functionally related compound(s) : 199
Total Number of Articles : 425
Description

nuclear receptor subfamily 3, group C, member 2

Gene Summary

Enables several functions, including DNA binding activity; identical protein binding activity; and steroid hormone receptor activity. Involved in regulation of cell population proliferation. Located in cytoplasm and nucleus. Is active in glutamatergic synapse; postsynaptic density, intracellular component; and presynaptic active zone cytoplasmic component. Human ortholog(s) of this gene implicated in autosomal dominant pseudohypoaldosteronism type 1 and pseudohypoaldosteronism. Orthologous to human NR3C2 (nuclear receptor subfamily 3 group C member 2). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • mineralocorticoid receptor
  • MR
  • Mineralocorticoid receptor (aldosterone receptor)
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Properties