Protein Name angiotensin I converting enzyme
Organism Rattus norvegicus
Gene ID 24310
Gene Symbol


UniProt P47820 (ACE_RAT)
Relationships Total Number of functionally related compound(s) : 947
Total Number of Articles : 2257

angiotensin I converting enzyme

Gene Summary

Enables heterocyclic compound binding activity; metallopeptidase activity; and peptidyl-dipeptidase activity. Involved in several processes, including animal organ development; negative regulation of transport; and response to corticosteroid. Located in several cellular components, including basal plasma membrane; brush border membrane; and sperm midpiece. Used to study several diseases, including artery disease (multiple); glomerulonephritis (multiple); kidney failure (multiple); lung disease (multiple); and proteinuria (multiple). Biomarker of several diseases, including artery disease (multiple); congenital diaphragmatic hernia; endomyocardial fibrosis; liver cirrhosis (multiple); and lung disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); gastrointestinal system cancer (multiple); heart valve disease (multiple); and lung disease (multiple). Orthologous to human ACE (angiotensin I converting enzyme). [provided by Alliance of Genome Resources, Apr 2022]

  • angiotensin-converting enzyme
  • Dipeptidyl carboxypeptidase 1 (Angiotensin I-converting enzyme)
  • angiotensin 1 converting enzyme 1
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