| Protein Name | nuclear receptor subfamily 3, group C, member 2 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 110784 |
| Gene Symbol | Nr3c2 |
| UniProt | A3KN90 (A3KN90_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
103
Total Number of Articles : 198 |
Description |
nuclear receptor subfamily 3, group C, member 2 |
| Gene Summary |
Enables steroid binding activity. Involved in several processes, including angiotensin-activated signaling pathway; regulation of blood volume by renal aldosterone; and regulation of potassium:proton exchanging ATPase activity. Acts upstream of or within intracellular sodium ion homeostasis and renal sodium excretion. Is active in GABA-ergic synapse and glutamatergic synapse. Is expressed in several structures, including central nervous system; genitourinary system; intestine; and trophectoderm. Used to study autosomal dominant pseudohypoaldosteronism type 1. Human ortholog(s) of this gene implicated in autosomal dominant pseudohypoaldosteronism type 1; opioid abuse; and pseudohypoaldosteronism. Orthologous to human NR3C2 (nuclear receptor subfamily 3 group C member 2). [provided by Alliance of Genome Resources, Jun 2025] |
| synonyms |
|
| Properties | |