bardoxolone methyl


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214 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 NFE2 like bZIP transcription factor 2 NF2L2_HUMAN NFE2L2 Homo sapiens 4780 2545 27
2 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 15
3 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 13
4 nuclear factor, erythroid derived 2, like 2 NF2L2_MOUSE Nfe2l2 Mus musculus 18024 2012 13
5 NFE2 like bZIP transcription factor 2 NF2L2_RAT Nfe2l2 Rattus norvegicus 83619 1416 11
6 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 11
7 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 9
8 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 8
9 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 7
10 heme oxygenase 1 HMOX1_HUMAN HMOX1 Homo sapiens 3162 1764 7
11 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 7
12 AKT serine/threonine kinase 1 AKT1_RAT Akt1 Rattus norvegicus 24185 2385 5
13 mitogen-activated protein kinase 8 MK08_HUMAN MAPK8 Homo sapiens 5599 2863 5
14 cytochrome c, somatic CYC_HUMAN CYCS Homo sapiens 54205 3740 5
15 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 5
16 lon peptidase 1, mitochondrial LONM_HUMAN LONP1 Homo sapiens 9361 120 4
17 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 4
18 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 4
19 TNF receptor superfamily member 10b TR10B_HUMAN TNFRSF10B Homo sapiens 8795 608 4
20 NAD(P)H quinone dehydrogenase 1 NQO1_HUMAN NQO1 Homo sapiens 1728 1064 4
21 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 4
22 telomerase reverse transcriptase TERT_HUMAN TERT Homo sapiens 7015 997 4
23 RELA proto-oncogene, NF-kB subunit TF65_HUMAN RELA Homo sapiens 5970 1514 4
24 annexin A5 ANXA5_HUMAN ANXA5 Homo sapiens 308 1785 4
25 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 4
26 thymoma viral proto-oncogene 1 AKT1_MOUSE Akt1 Mus musculus 11651 3034 4
27 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 3
28 CD34 molecule CD34_HUMAN CD34 Homo sapiens 947 1218 3
29 superoxide dismutase 1 SODC_HUMAN SOD1 Homo sapiens 6647 2118 3
30 C-C motif chemokine ligand 2 CCL2_HUMAN CCL2 Homo sapiens 6347 1858 3
31 MYC proto-oncogene, bHLH transcription factor MYC_HUMAN MYC Homo sapiens 4609 2261 3
32 BCL2 like 1 B2CL1_HUMAN BCL2L1 Homo sapiens 598 1360 3
33 NFKB inhibitor alpha IKBA_HUMAN NFKBIA Homo sapiens 4792 1043 3
34 caspase 8 CASP8_HUMAN CASP8 Homo sapiens 841 1641 3
35 signal transducer and activator of transcription 3 STAT3_MOUSE Stat3 Mus musculus 20848 1288 3
36 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 3
37 cyclin D1 CCND1_HUMAN CCND1 Homo sapiens 595 1747 3
38 ubiquitin like 5 UBL5_HUMAN UBL5 Homo sapiens 59286 75 3
39 tumor necrosis factor receptor superfamily, member 25 Q8VD70_MOUSE Tnfrsf25 Mus musculus 85030 159 2
40 tumor necrosis factor TNFA_MOUSE Tnf Mus musculus 21926 5931 2
41 phosphatase and tensin homolog O54857_RAT Pten Rattus norvegicus 50557 319 2
42 caspase 9 CASP9_HUMAN CASP9 Homo sapiens 842 1801 2
43 SRC proto-oncogene, non-receptor tyrosine kinase SRC_HUMAN SRC Homo sapiens 6714 2142 2
44 peroxisome proliferator activated receptor gamma PPARG_HUMAN PPARG Homo sapiens 5468 2156 2
45 glutamate-cysteine ligase modifier subunit GSH0_HUMAN GCLM Homo sapiens 2730 116 2
46 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 2
47 carbonic anhydrase 1 CAH1_RAT Car1 Rattus norvegicus 310218 1725 2
48 kelch like ECH associated protein 1 KEAP1_HUMAN KEAP1 Homo sapiens 9817 659 2
49 interleukin 10 IL10_MOUSE Il10 Mus musculus 16153 1965 2
50 mitogen activated protein kinase 3 MK03_RAT Mapk3 Rattus norvegicus 50689 1665 2