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135 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 26
2 caspase 8 CASP8_HUMAN CASP8 Homo sapiens 841 1641 17
3 cytochrome c, somatic CYC_HUMAN CYCS Homo sapiens 54205 3740 14
4 caspase 1 CASP1_HUMAN CASP1 Homo sapiens 834 952 12
5 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 11
6 TNF superfamily member 10 TNF10_HUMAN TNFSF10 Homo sapiens 8743 1439 10
7 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 9
8 caspase 9 CASP9_HUMAN CASP9 Homo sapiens 842 1801 7
9 caspase 3 CASP3_MOUSE Casp3 Mus musculus 12367 1791 5
10 receptor interacting serine/threonine kinase 1 RIPK1_HUMAN RIPK1 Homo sapiens 8737 356 4
11 tumor necrosis factor TNFA_MOUSE Tnf Mus musculus 21926 5931 4
12 caspase 1 CASP1_MOUSE Casp1 Mus musculus 12362 685 4
13 caspase 3 CASP3_RAT Casp3 Rattus norvegicus 25402 2178 4
14 cathepsin B CATB_HUMAN CTSB Homo sapiens 1508 1121 3
15 poly (ADP-ribose) polymerase family, member 1 Q921K2_MOUSE Parp1 Mus musculus 11545 842 3
16 mixed lineage kinase domain like pseudokinase MLKL_HUMAN MLKL Homo sapiens 197259 160 3
17 collagen type XI alpha 2 chain COBA2_HUMAN COL11A2 Homo sapiens 1302 794 3
18 caspase 8 CASP8_RAT Casp8 Rattus norvegicus 64044 314 3
19 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 3
20 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 3
21 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 3
22 receptor interacting serine/threonine kinase 3 RIPK3_HUMAN RIPK3 Homo sapiens 11035 184 3
23 CASP8 and FADD like apoptosis regulator CFLAR_HUMAN CFLAR Homo sapiens 8837 339 3
24 beclin 1 BECN1_HUMAN BECN1 Homo sapiens 8678 847 3
25 interleukin 1 beta IL1B_HUMAN IL1B Homo sapiens 3553 3575 2
26 gelsolin GELS_HUMAN GSN Homo sapiens 2934 300 2
27 interleukin 1 alpha IL1A_HUMAN IL1A Homo sapiens 3552 2741 2
28 X-linked inhibitor of apoptosis XIAP_HUMAN XIAP Homo sapiens 331 647 2
29 receptor-interacting serine-threonine kinase 3 RIPK3_MOUSE Ripk3 Mus musculus 56532 173 2
30 transforming growth factor, beta 1 TGFB1_RAT Tgfb1 Rattus norvegicus 59086 1730 2
31 RELA proto-oncogene, NF-kB subunit TF65_HUMAN RELA Homo sapiens 5970 1514 2
32 caspase 2 CASP2_HUMAN CASP2 Homo sapiens 835 320 2
33 B cell leukemia/lymphoma 2 BCL2_MOUSE Bcl2 Mus musculus 12043 1497 2
34 caspase 1 Q91W32_RAT Casp1 Rattus norvegicus 25166 367 2
35 transformation related protein 53, pseudogene - Trp53-ps Mus musculus 22060 1552 2
36 Fas cell surface death receptor TNR6_HUMAN FAS Homo sapiens 355 474 2
37 amyloid beta (A4) precursor protein A4_MOUSE App Mus musculus 11820 1407 2
38 interleukin 18 IL18_HUMAN IL18 Homo sapiens 3606 686 2
39 interleukin 4 IL4_HUMAN IL4 Homo sapiens 3565 1529 1
40 interleukin 5 IL5_HUMAN IL5 Homo sapiens 3567 698 1
41 apolipoprotein E APOE_HUMAN APOE Homo sapiens 348 1088 1
42 interleukin 1 alpha IL1A_RAT Il1a Rattus norvegicus 24493 1116 1
43 SYF2 pre-mRNA splicing factor SYF2_HUMAN SYF2 Homo sapiens 25949 64 1
44 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 1
45 CD8a molecule CD8A_HUMAN CD8A Homo sapiens 925 1925 1
46 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 NFKB1_MOUSE Nfkb1 Mus musculus 18033 3161 1
47 amyloid beta precursor protein A4_HUMAN APP Homo sapiens 351 3390 1
48 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 1
49 perforin 1 PERF_HUMAN PRF1 Homo sapiens 5551 94 1
50 Fos proto-oncogene, AP-1 transcription factor subunit FOS_HUMAN FOS Homo sapiens 2353 1431 1