Protein Name gelsolin
Organism Homo sapiens
Gene ID 2934
Gene Symbol


UniProt P06396 (GELS_HUMAN), A0A0A0MS51 (A0A0A0MS51_HUMAN), A0A384MEF1 (A0A384MEF1_HUMAN), A0A0A0MT01 (A0A0A0MT01_HUMAN), B7Z4U6 (B7Z4U6_HUMAN)
Relationships Total Number of functionally related compound(s) : 300
Total Number of Articles : 406


Gene Summary

The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

  • gelsolin
  • actin-depolymerizing factor
  • brevin
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