Protein Name interleukin 1 alpha
Organism Rattus norvegicus
Gene ID 24493
Gene Symbol


UniProt P16598 (IL1A_RAT)
Relationships Total Number of functionally related compound(s) : 1116
Total Number of Articles : 1665

interleukin 1 alpha

Gene Summary

Predicted to enable copper ion binding activity; cytokine activity; and interleukin-1 receptor binding activity. Involved in several processes, including keratinization; negative regulation of establishment of Sertoli cell barrier; and positive regulation of intracellular signal transduction. Located in several cellular components, including cell surface; cytosol; and extracellular space. Used to study interstitial lung disease. Biomarker of several diseases, including endometritis; lung disease (multiple); urinary tract infection; uveitis; and varicocele. Human ortholog(s) of this gene implicated in several diseases, including Fabry disease; Schnitzler syndrome; autoimmune disease (multiple); hematologic cancer (multiple); and lung disease (multiple). Orthologous to human IL1A (interleukin 1 alpha). [provided by Alliance of Genome Resources, Apr 2022]

  • interleukin-1 alpha
  • IL-1 alpha
  • IL-1F1
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