parthenolide


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352 Functionally related protein(s)
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Protein Name
UniProt Entry
Gene Symbol
Organism
NCBI Gene ID
# All related compound(s)
#Article(s)
1 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 95
2 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 NFKB1_MOUSE Nfkb1 Mus musculus 18033 3161 33
3 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 20
4 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 19
5 RELA proto-oncogene, NF-kB subunit TF65_HUMAN RELA Homo sapiens 5970 1514 15
6 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 13
7 tumor necrosis factor TNFA_MOUSE Tnf Mus musculus 21926 5931 12
8 C-X-C motif chemokine ligand 8 IL8_HUMAN CXCL8 Homo sapiens 3576 4038 12
9 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 11
10 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 11
11 NFKB inhibitor alpha IKBA_HUMAN NFKBIA Homo sapiens 4792 1043 10
12 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 10
13 interleukin 1 beta IL1B_HUMAN IL1B Homo sapiens 3553 3575 9
14 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 9
15 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 9
16 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 9
17 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 9
18 tumor necrosis factor TNFA_RAT Tnf Rattus norvegicus 24835 3922 8
19 cytochrome c, somatic CYC_HUMAN CYCS Homo sapiens 54205 3740 7
20 intercellular adhesion molecule 1 ICAM1_HUMAN ICAM1 Homo sapiens 3383 1840 7
21 mitogen-activated protein kinase 8 MK08_HUMAN MAPK8 Homo sapiens 5599 2863 7
22 signal transducer and activator of transcription 3 STAT3_MOUSE Stat3 Mus musculus 20848 1288 7
23 matrix metallopeptidase 9 MMP9_HUMAN MMP9 Homo sapiens 4318 2470 7
24 latexin LXN_HUMAN LXN Homo sapiens 56925 5329 7
25 BCL2 like 1 B2CL1_HUMAN BCL2L1 Homo sapiens 598 1360 6
26 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 6
27 histone deacetylase 1 HDAC1_HUMAN HDAC1 Homo sapiens 3065 486 6
28 caspase 8 CASP8_HUMAN CASP8 Homo sapiens 841 1641 6
29 NFE2 like bZIP transcription factor 2 NF2L2_HUMAN NFE2L2 Homo sapiens 4780 2545 6
30 tumor necrosis factor (ligand) superfamily, member 12 TNF12_MOUSE Tnfsf12 Mus musculus 21944 55 6
31 C-C motif chemokine ligand 2 CCL2_HUMAN CCL2 Homo sapiens 6347 1858 6
32 catenin beta 1 CTNB1_HUMAN CTNNB1 Homo sapiens 1499 2350 5
33 v-rel reticuloendotheliosis viral oncogene homolog A (avian) TF65_MOUSE Rela Mus musculus 19697 993 5
34 cardiotrophin 1 CTF1_HUMAN CTF1 Homo sapiens 1489 180 5
35 TNF superfamily member 10 TNF10_HUMAN TNFSF10 Homo sapiens 8743 1439 5
36 interleukin 6 IL6_MOUSE Il6 Mus musculus 16193 3985 5
37 GLI family zinc finger 2 GLI2_HUMAN GLI2 Homo sapiens 2736 1670 5
38 caspase 9 CASP9_HUMAN CASP9 Homo sapiens 842 1801 5
39 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 5
40 interleukin 6 IL6_RAT Il6 Rattus norvegicus 24498 2269 4
41 nitric oxide synthase 2 NOS2_RAT Nos2 Rattus norvegicus 24599 1861 4
42 interleukin 1 beta IL1B_MOUSE Il1b Mus musculus 16176 2626 4
43 BH3 interacting domain death agonist BID_HUMAN BID Homo sapiens 637 1130 4
44 NFKB inhibitor alpha IKBA_RAT Nfkbia Rattus norvegicus 25493 441 4
45 nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha IKBA_MOUSE Nfkbia Mus musculus 18035 734 4
46 prostaglandin-endoperoxide synthase 2 PGH2_RAT Ptgs2 Rattus norvegicus 29527 1161 4
47 phosphatase and tensin homolog PTEN_HUMAN PTEN Homo sapiens 5728 1316 4
48 chemokine (C-C motif) ligand 2 CCL2_MOUSE Ccl2 Mus musculus 20296 1060 4
49 vascular cell adhesion molecule 1 VCAM1_HUMAN VCAM1 Homo sapiens 7412 1154 3
50 toll like receptor 4 TLR4_HUMAN TLR4 Homo sapiens 7099 1426 3