parthenolide

nuclear factor kappa B subunit 1 ; Homo sapiens







95 Article(s)
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1 34405014 Suppression Of Aberrant Activation Of NF-κB Pathway In Drug-resistant Leukemia Stem Cells Contributes To Parthenolide-potentiated Reversal Of Drug Resistance In Leukemia. 2021 5
2 34575860 Cyclosporine A and Tacrolimus Induce Functional Impairment and Inflammatory Reactions in Endothelial Progenitor Cells. 2021 Sep 8 1
3 32250214 The Anti-inflammatory Potential of Selected Plant-derived Compounds in Respiratory Diseases. 2020 1
4 32751648 Parthenolide Has Negative Effects on In Vitro Enhanced Osteogenic Phenotypes by Inflammatory Cytokine TNF-α via Inhibiting JNK Signaling. 2020 Jul 30 2
5 32823992 Parthenolide as Cooperating Agent for Anti-Cancer Treatment of Various Malignancies. 2020 Aug 14 2
6 32887995 Update on the Role of NFκB in Promoting Aggressive Phenotypes of Estrogen Receptor-Positive Breast Cancer. 2020 Oct 1 1
7 33258341 Parthenolide increases the sensitivity of gastric cancer cells to chemotherapy. 2020 Dec 1
8 31164821 Collateral Sensitivity of Parthenolide via NF-κB and HIF-α Inhibition and Epigenetic Changes in Drug-Resistant Cancer Cell Lines. 2019 1
9 31608008 TLR4/NF-κB Signaling Induces GSDMD-Related Pyroptosis in Tubular Cells in Diabetic Kidney Disease. 2019 1
10 29705182 Inhibition of NF-κB results in anti-glioma activity and reduces temozolomide-induced chemoresistance by down-regulating MGMT gene expression. 2018 Aug 1 1
11 30079458 Parthenolide and DMAPT induce cell death in primitive CML cells through reactive oxygen species. 2018 Oct 1
12 28108625 Combined Parthenolide and Balsalazide Have Enhanced Antitumor Efficacy Through Blockade of NF-κB Activation. 2017 Feb 6
13 28782644 DMAPT inhibits NF-κB activity and increases sensitivity of prostate cancer cells to X-rays in vitro and in tumor xenografts in vivo. 2017 Nov 2
14 28829282 Parthenolide Promotes Differentiation of Osteoblasts Through the Wnt/β-Catenin Signaling Pathway in Inflammatory Environments. 2017 Sep 6
15 28965856 Pharmacological evidence for the bone-autonomous contribution of the NFκB/β-catenin axis to breast cancer related osteolysis. 2017 Dec 1 2
16 29050271 Sesquiterpene binding Gly-Leu-Ser/Lys-"co-adaptation pocket" to inhibit lung cancer cell epithelial-mesenchymal transition. 2017 Sep 19 1
17 26821066 The clerodane diterpene casearin J induces apoptosis of T-ALL cells through SERCA inhibition, oxidative stress, and interference with Notch1 signaling. 2016 Jan 28 5
18 27757770 Protective effect of sesquiterpene lactone parthenolide on LPS-induced acute lung injury. 2016 Dec 1
19 25553117 Parthenolide inhibits cancer stem-like side population of nasopharyngeal carcinoma cells via suppression of the NF-κB/COX-2 pathway. 2015 4
20 25611383 NF-κB-dependent and -independent epigenetic modulation using the novel anti-cancer agent DMAPT. 2015 Jan 22 2
21 25971793 Sesquiterpene lactone parthenolide attenuates production of inflammatory mediators by suppressing the Toll-like receptor-4-mediated activation of the Akt, mTOR, and NF-κB pathways. 2015 Sep 4
22 26072071 Inhibitory effects of parthenolide on the activity of NF-κB in multiple myeloma via targeting TRAF6. 2015 Jun 5
23 26160345 On involvement of transcription factors nuclear factor kappa-light-chain-enhancer of activated B cells, activator protein-1 and signal transducer and activator of transcription-3 in photodynamic therapy-induced death of crayfish neurons and satellite glial cells. 2015 Jul 1
24 26206887 Lyso-Gb3 activates Notch1 in human podocytes. 2015 Oct 15 4
25 27122844 Parthenolide-Induced Cytotoxicity in H9c2 Cardiomyoblasts Involves Oxidative Stress. 2015 Jan 1
26 23383347 Epidermal growth factor protects squamous cell carcinoma against cisplatin-induced cytotoxicity through increased interleukin-1β expression. 2013 1
27 23575899 NF-κB pathway contributes to cadmium-induced apoptosis of porcine granulosa cells. 2013 Jun 1
28 23792430 Parthenolide reverses doxorubicin resistance in human lung carcinoma A549 cells by attenuating NF-κB activation and HSP70 up-regulation. 2013 Aug 14 1
29 23898080 Parthenolide complements the cell death-inducing activity of doxorubicin in melanoma cells. 2013 Aug 2
30 23999007 Fn14 in podocytes and proteinuric kidney disease. 2013 Dec 2
31 24080940 Age sensitivity of NFκB abundance and programmed cell death in erythrocytes induced by NFκB inhibitors. 2013 2
32 22105338 Potential roles of the NFκB and glutathione pathways in mature human erythrocytes. 2012 Mar 1
33 22155272 Bcl-XL, but not Bcl-2, can protect human B-lymphoma cell lines from parthenolide-induced apoptosis. 2012 May 1 1
34 22238372 Oxysterols exert proinflammatory effects in placental trophoblasts via TLR4-dependent, cholesterol-sensitive activation of NF-κB. 2012 Jul 1
35 22683888 TNF-α inhibits PPARβ/δ activity and SIRT1 expression through NF-κB in human adipocytes. 2012 Sep 2
36 23039130 Involvement of Akt/NF-κB pathway in antitumor effects of parthenolide on glioblastoma cells in vitro and in vivo. 2012 Oct 5 4
37 20870895 Molecular pathways of spontaneous and TNF-{alpha}-mediated neutrophil apoptosis under intermittent hypoxia. 2011 Jul 1
38 21289336 Parthenolide, an NF-κB inhibitor, suppresses tumor growth and enhances response to chemotherapy in gastric cancer. 2011 Jan-Feb 5
39 21325821 The NFĸB pathway inhibitors Bay 11-7082 and parthenolide induce programmed cell death in anucleated Erythrocytes. 2011 5
40 21625432 The interplay between NF-kappaB and E2F1 coordinately regulates inflammation and metabolism in human cardiac cells. 2011 2
41 21992677 Parthenolide inhibits ERK and AP-1 which are dysregulated and contribute to excessive IL-8 expression and secretion in cystic fibrosis cells. 2011 Oct 12 1
42 19774508 Sesquiterpene lactone parthenolide markedly enhances sensitivity of human A549 cells to low-dose oxaliplatin via inhibition of NF-kappaB activation and induction of apoptosis. 2010 Feb 3
43 19821157 Pim-2 activates API-5 to inhibit the apoptosis of hepatocellular carcinoma cells through NF-kappaB pathway. 2010 Jun 3
44 19943112 NF-kappaB activation is required for apoptosis in fibrocystin/polyductin-depleted kidney epithelial cells. 2010 Jan 1
45 20151982 Up-regulation of pro-inflammatory genes as adaptation to hypoxia in MCF-7 cells and in human mammary invasive carcinoma microenvironment. 2010 Apr 1
46 20209491 A water-soluble parthenolide analogue suppresses in vivo prostate cancer growth by targeting NFkappaB and generating reactive oxygen species. 2010 Jul 1 1
47 20434582 Chlamydial infection of monocytes stimulates IL-1beta secretion through activation of the NLRP3 inflammasome. 2010 Aug 1
48 20540695 Protecting skin photoaging by NF-kappaB inhibitor. 2010 Jun 1 2
49 20582811 Natural products inhibit LPS-induced activation of pro-inflammatory cytokines in peripheral blood mononuclear cells. 2010 Jul 1
50 20590608 Cell context-dependent activities of parthenolide in primary and metastatic melanoma cells. 2010 Jul 3