parthenolide

nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 ; Mus musculus







33 Article(s)
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1 34004586 Design, synthesis and in vivo anticancer activity of novel parthenolide and micheliolide derivatives as NF-κB and STAT3 inhibitors. 2021 Jun 1
2 32299536 NF-κB Inhibitor Parthenolide Promotes Renal Tubules Albumin Uptake in Type 2 Diabetic Nephropathy. 2020 Mar 31 1
3 33083018 Parthenolide promotes the repair of spinal cord injury by modulating M1/M2 polarization via the NF-κB and STAT 1/3 signaling pathway. 2020 1
4 29936575 Chronic low dose ethanol induces an aggressive metastatic phenotype in TRAMP mice, which is counteracted by parthenolide. 2018 Oct 2
5 30066289 Inhibition of NF-κB Reduces Renal Inflammation and Expression of PEPCK in Type 2 Diabetic Mice. 2018 Dec 2
6 28965856 Pharmacological evidence for the bone-autonomous contribution of the NFκB/β-catenin axis to breast cancer related osteolysis. 2017 Dec 1 1
7 25664142 Sesquiterpene lactones inhibit advanced oxidation protein product-induced MCP-1 expression in podocytes via an IKK/NF-κB-dependent mechanism. 2015 1
8 24440756 Role of ERK/NFκB in vanadium (IV) oxide mediated osteoblast differentiation in C3H10t1/2 cells. 2014 Jun 1
9 24075100 The TGFβ1 pathway is required for NFκB dependent gene expression in mouse keratinocytes. 2013 Dec 2
10 22155740 Parthenolide, an inhibitor of the nuclear factor-κB pathway, ameliorates dextran sulfate sodium-induced colitis in mice. 2012 Jan 2
11 21719790 The inflammatory cytokines TWEAK and TNFα reduce renal klotho expression through NFκB. 2011 Jul 1
12 20554912 Angiotensin II-induced upregulation of AT(1) receptor expression: sequential activation of NF-kappaB and Elk-1 in neurons. 2010 Sep 1
13 19095747 JP-8 induces immune suppression via a reactive oxygen species NF-kappabeta-dependent mechanism. 2009 Mar 1
14 19423687 CTGF promotes inflammatory cell infiltration of the renal interstitium by activating NF-kappaB. 2009 Jul 1
15 19555300 Can we predict the effects of NF-kappaB inhibition in sepsis? Studies with parthenolide and ethyl pyruvate. 2009 Aug 2
16 18235096 The cytokine TWEAK modulates renal tubulointerstitial inflammation. 2008 Apr 1
17 17200339 Parthenolide, a natural inhibitor of Nuclear Factor-kappaB, inhibits lung colonization of murine osteosarcoma cells. 2007 Jan 1 3
18 17349210 TNF-alpha induces transient resistance to Fas-induced apoptosis in eosinophilic acute myeloid leukemia cells. 2007 Feb 1
19 17436572 Understanding interactions between and among apoptosis inducing pathways in tumor cells. 2007 Mar-Apr 1
20 17947709 Hsp72 induces inflammation and regulates cytokine production in airway epithelium through a TLR4- and NF-kappaB-dependent mechanism. 2007 Nov 1 1
21 16223857 Palmitate induces tumor necrosis factor-alpha expression in C2C12 skeletal muscle cells by a mechanism involving protein kinase C and nuclear factor-kappaB activation. 2006 Jan 1
22 16461558 Suppressive effects of dehydroepiandrosterone and the nuclear factor-kappaB inhibitor parthenolide on corticotroph tumor cell growth and function in vitro and in vivo. 2006 Feb 1
23 16720096 Parthenolide has limited effects on nuclear factor-kappa beta increases and worsens survival in lipopolysaccharide-challenged C57BL/6J mice. 2006 Mar 21 5
24 16741149 Parthenolide modulates the NF-kappaB-mediated inflammatory responses in experimental atherosclerosis. 2006 Aug 5
25 16027228 Prevention of the ultraviolet B-mediated skin photoaging by a nuclear factor kappaB inhibitor, parthenolide. 2005 Nov 4
26 15153562 Angiotensin II, via AT1 and AT2 receptors and NF-kappaB pathway, regulates the inflammatory response in unilateral ureteral obstruction. 2004 Jun 1
27 15475494 Lipopolysaccharide increases alveolar type II cell number in fetal mouse lungs through Toll-like receptor 4 and NF-kappaB. 2004 Nov 1
28 12504894 Methylglyoxal-bovine serum albumin stimulates tumor necrosis factor alpha secretion in RAW 264.7 cells through activation of mitogen-activating protein kinase, nuclear factor kappaB and intracellular reactive oxygen species formation. 2003 Jan 15 3
29 14726605 Regulation of expression of stromyelysin-1 by proinflammatory cytokines in mouse brain astrocytes. 2003 Dec 1
30 12552998 Lactacystin, a proteasome inhibitor, potentiates the apoptotic effect of parthenolide, an inhibitor of NFkappaB activation, on drug-resistant mouse leukemia L1210 cells. 2002 Nov-Dec 1
31 11301852 A sesquiterpene lactone, costunolide, from Magnolia grandiflora inhibits NF-kappa B by targeting I kappa B phosphorylation. 2001 Mar 3
32 11911251 Augmentation of apoptosis responses in p53-deficient L1210 cells by compounds directed at blocking NFkappaB activation. 2001 Nov-Dec 1
33 10858246 Requirement for NF-kappaB in transcriptional activation of monocyte chemotactic protein 1 by Chlamydia pneumoniae in human endothelial cells. 2000 Jul 1