Imatinib Mesylate


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1461 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 ABL proto-oncogene 1, non-receptor tyrosine kinase ABL1_HUMAN ABL1 Homo sapiens 25 989 1908
2 KIT proto-oncogene, receptor tyrosine kinase KIT_HUMAN KIT Homo sapiens 3815 679 1113
3 platelet derived growth factor receptor alpha PGFRA_HUMAN PDGFRA Homo sapiens 5156 229 387
4 platelet derived growth factor receptor beta PGFRB_HUMAN PDGFRB Homo sapiens 5159 417 350
5 BCR activator of RhoGEF and GTPase BCR_HUMAN BCR Homo sapiens 613 263 229
6 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 123
7 factor interacting with PAPOLA and CPSF1 FIP1_HUMAN FIP1L1 Homo sapiens 81608 167 117
8 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 109
9 c-abl oncogene 1, non-receptor tyrosine kinase ABL1_MOUSE Abl1 Mus musculus 11350 160 109
10 KIT proto-oncogene receptor tyrosine kinase KIT_MOUSE Kit Mus musculus 16590 294 96
11 CD34 molecule CD34_HUMAN CD34 Homo sapiens 947 1218 77
12 ATP binding cassette subfamily G member 2 (Junior blood group) ABCG2_HUMAN ABCG2 Homo sapiens 9429 1370 63
13 solute carrier family 22 member 1 S22A1_HUMAN SLC22A1 Homo sapiens 6580 415 63
14 platelet derived growth factor receptor, beta polypeptide PGFRB_MOUSE Pdgfrb Mus musculus 18596 179 62
15 KIT ligand SCF_HUMAN KITLG Homo sapiens 4254 644 48
16 signal transducer and activator of transcription 5A STA5A_HUMAN STAT5A Homo sapiens 6776 575 45
17 SRC proto-oncogene, non-receptor tyrosine kinase SRC_HUMAN SRC Homo sapiens 6714 2142 44
18 interferon alpha 1 IFNA1_HUMAN IFNA1 Homo sapiens 3439 1490 43
19 BCR activator of RhoGEF and GTPase BCR_MOUSE Bcr Mus musculus 110279 102 41
20 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 39
21 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 38
22 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 37
23 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 37
24 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 37
25 TXK tyrosine kinase TXK_HUMAN TXK Homo sapiens 7294 195 37
26 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 37
27 platelet derived growth factor receptor, alpha polypeptide PGFRA_MOUSE Pdgfra Mus musculus 18595 112 34
28 catenin beta 1 CTNB1_HUMAN CTNNB1 Homo sapiens 1499 2350 34
29 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 32
30 LYN proto-oncogene, Src family tyrosine kinase LYN_HUMAN LYN Homo sapiens 4067 285 31
31 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 29
32 transforming growth factor beta 1 TGFB1_HUMAN TGFB1 Homo sapiens 7040 2953 26
33 Janus kinase 2 JAK2_HUMAN JAK2 Homo sapiens 3717 1038 25
34 colony stimulating factor 1 receptor CSF1R_HUMAN CSF1R Homo sapiens 1436 231 24
35 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 24
36 ETS variant transcription factor 6 ETV6_HUMAN ETV6 Homo sapiens 2120 167 24
37 MYC proto-oncogene, bHLH transcription factor MYC_HUMAN MYC Homo sapiens 4609 2261 23
38 MCL1 apoptosis regulator, BCL2 family member MCL1_HUMAN MCL1 Homo sapiens 4170 1015 22
39 mitogen-activated protein kinase 14 MK14_HUMAN MAPK14 Homo sapiens 1432 3132 22
40 BCL2 like 1 B2CL1_HUMAN BCL2L1 Homo sapiens 598 1360 22
41 ret proto-oncogene RET_HUMAN RET Homo sapiens 5979 674 21
42 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 21
43 CRK like proto-oncogene, adaptor protein CRKL_HUMAN CRKL Homo sapiens 1399 58 20
44 platelet derived growth factor subunit B PDGFB_HUMAN PDGFB Homo sapiens 5155 216 20
45 heat shock protein 90 alpha family class A member 1 HS90A_HUMAN HSP90AA1 Homo sapiens 3320 1552 19
46 phosphoglycolate phosphatase PGP_HUMAN PGP Homo sapiens 283871 1342 18
47 latexin LXN_HUMAN LXN Homo sapiens 56925 5329 16
48 TNF superfamily member 10 TNF10_HUMAN TNFSF10 Homo sapiens 8743 1439 14
49 fms related receptor tyrosine kinase 3 FLT3_HUMAN FLT3 Homo sapiens 2322 569 14
50 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 14