Imatinib Mesylate

platelet derived growth factor receptor, beta polypeptide ; Mus musculus







62 Article(s)
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1 33357774 Reactive pericytes in early phase are involved in glial activation and late-onset hypersusceptibility to pilocarpine-induced seizures in traumatic brain injury model mice. 2021 Jan 1
2 33539723 Pathologic HIF1α signaling drives adipose progenitor dysfunction in obesity. 2021 Apr 1 1
3 33753340 RNA Interference Screening Reveals Requirement for Platelet-Derived Growth Factor Receptor Beta in Japanese Encephalitis Virus Infection. 2021 May 18 1
4 33784254 Thymosin β4 protects against aortic aneurysm via endocytic regulation of growth factor signaling. 2021 May 17 1
5 32260484 Imatinib Sets Pericyte Mosaic in the Retina. 2020 Apr 5 1
6 31135065 A pericyte-glia scarring develops at the leaky capillaries in the hippocampus during seizure activity. 2019 Jul 2
7 31645346 Novel PDGFRB rearrangement in multifocal infantile myofibromatosis is tumorigenic and sensitive to imatinib. 2019 Oct 1
8 30007969 Imatinib Ameliorated Retinal Neovascularization by Suppressing PDGFR-α and PDGFR-β. 2018 1
9 28139720 Inhibition of PDGFR signaling prevents muscular fatty infiltration after rotator cuff tear in mice. 2017 Jan 31 1
10 26703895 Ph-like ALL-related novel fusion kinase ATF7IP-PDGFRB exhibits high sensitivity to tyrosine kinase inhibitors in murine cells. 2016 Mar 1
11 27918111 Imatinib accelerates progenitor cell-mediated liver regeneration in choline-deficient ethionine-supplemented diet-fed mice. 2016 Oct 2
12 27942010 Limited Impact of Imatinib in a Murine Model of Sclerodermatous Chronic Graft-versus-Host Disease. 2016 1
13 26276287 Effect of PDGF-Rb antagonist imatinib on endometrial injury repairing in mouse model. 2015 Jul 3
14 24599309 Imatinib mesylate exerts anti-proliferative effects on osteosarcoma cells and inhibits the tumour growth in immunocompetent murine models. 2014 1
15 24848114 Indispensable functions of ABL and PDGF receptor kinases in epithelial adherence of attaching/effacing pathogens under physiological conditions. 2014 Jul 15 1
16 24885373 Role of platelet-derived growth factor/platelet-derived growth factor receptor axis in the trafficking of circulating fibrocytes in pulmonary fibrosis. 2014 Dec 3
17 24981766 Expression of platelet-derived growth factor receptor β is maintained by Prox1 in lymphatic endothelial cells and is required for tumor lymphangiogenesis. 2014 Sep 1
18 25243742 A differential role for CD248 (Endosialin) in PDGF-mediated skeletal muscle angiogenesis. 2014 1
19 25253994 Inhibition of proliferation and migration of luminal and claudin-low breast cancer cells by PDGFR inhibitors. 2014 1
20 23083077 Inhibition of radiation-induced skin fibrosis with imatinib. 2013 Mar 1
21 23087024 Imatinib attenuates hypoxia-induced pulmonary arterial hypertension pathology via reduction in 5-hydroxytryptamine through inhibition of tryptophan hydroxylase 1 expression. 2013 Jan 1 2
22 23591991 Smooth muscle hyperplasia due to loss of smooth muscle α-actin is driven by activation of focal adhesion kinase, altered p53 localization and increased levels of platelet-derived growth factor receptor-β. 2013 Aug 1 1
23 23787115 Effect of tyrosine kinase inhibitors, imatinib and nilotinib, in murine lipopolysaccharide-induced acute lung injury during neutropenia recovery. 2013 Jun 20 1
24 21911014 Imatinib-ULS-lysozyme: a proximal tubular cell-targeted conjugate of imatinib for the treatment of renal diseases. 2012 Feb 10 3
25 22940072 Combined inhibition of c-Abl and PDGF receptors for prevention and treatment of murine sclerodermatous chronic graft-versus-host disease. 2012 Nov 2
26 21181412 Time-specific blockade of PDGFR with Imatinib (Glivec®) causes cataract and disruption of lens fiber cells in neonatal mice. 2011 Mar 5
27 21188449 Comparative suppressive effects of tyrosine kinase inhibitors imatinib and nilotinib in models of autoimmune arthritis. 2011 Jun 2
28 21387285 Anti-stromal therapy with imatinib inhibits growth and metastasis of gastric carcinoma in an orthotopic nude mouse model. 2011 May 1 2
29 21659722 Effect of nilotinib on bleomycin-induced acute lung injury and pulmonary fibrosis in mice. 2011 4
30 21716259 Platelet-derived growth factor receptor signaling activates pericyte-myofibroblast transition in obstructive and post-ischemic kidney fibrosis. 2011 Dec 1
31 21847523 Tyrosine kinase inhibitors ameliorate autoimmune encephalomyelitis in a mouse model of multiple sclerosis. 2011 Dec 2
32 22034611 Hypoxic pulmonary hypertension in mice with constitutively active platelet-derived growth factor receptor-β. 2011 Apr-Jun 3
33 22204395 Tyrosine kinase chromosomal translocations mediate distinct and overlapping gene regulation events. 2011 Dec 28 1
34 20067864 HPLC determination of imatinib in plasma and tissues after multiple oral dose administration to mice. 2010 Jan 1
35 20181277 c-Fms-mediated differentiation and priming of monocyte lineage cells play a central role in autoimmune arthritis. 2010 2
36 20610572 PDGF beta-receptor kinase activity and ERK1/2 mediate glycosaminoglycan elongation on biglycan and increases binding to LDL. 2010 Sep 1
37 19289603 Imatinib attenuates skeletal muscle dystrophy in mdx mice. 2009 Aug 1
38 19801450 Tie2-mediated loss of peroxisome proliferator-activated receptor-gamma in mice causes PDGF receptor-beta-dependent pulmonary arterial muscularization. 2009 Dec 1
39 18816866 Macromolecular dynamic contrast-enhanced (DCE)-MRI detects reduced vascular permeability in a prostate cancer bone metastasis model following anti-platelet-derived growth factor receptor (PDGFR) therapy, indicating a drop in vascular endothelial growth factor receptor (VEGFR) activation. 2008 Oct 1
40 17200369 Emerging role of platelet-derived growth factor receptor-beta inhibition in radioimmunotherapy of experimental pancreatic cancer. 2007 Jan 1 1
41 17504974 The 5-HT transporter transactivates the PDGFbeta receptor in pulmonary artery smooth muscle cells. 2007 Sep 3
42 17663639 Imatinib promotes osteoblast differentiation by inhibiting PDGFR signaling and inhibits osteoclastogenesis by both direct and stromal cell-dependent mechanisms. 2007 Nov 7
43 17691110 Identification of a subset of pericytes that respond to combination therapy targeting PDGF and VEGF signaling. 2007 Dec 15 1
44 17694264 Imatinib mesylate both prevents and treats the arthritis induced by type II collagen antibody in mice. 2007 4
45 17712313 Treatment with imatinib improves drug delivery and efficacy in NSCLC xenografts. 2007 Sep 17 1
46 17849262 Imatinib mesylate inhibits fibrogenesis in asbestos-induced interstitial pneumonia. 2007 Sep 2
47 17986854 PDGFRbeta and HIF-1alpha inhibition with imatinib and radioimmunotherapy of experimental prostate cancer. 2007 Nov 2
48 16274936 STI571 (Gleevec) improves tumor growth delay and survival in irradiated mouse models of glioblastoma. 2006 Jan 1 2
49 16757703 Targeting platelet-derived growth factor receptor on endothelial cells of multidrug-resistant prostate cancer. 2006 Jun 7 1
50 17148686 Platelet-derived growth factor-beta receptor activation is essential for fibroblast and pericyte recruitment during cutaneous wound healing. 2006 Dec 1