| Protein Name | solute carrier family 22 member 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 6580 |
| Gene Symbol | SLC22A1 |
| UniProt | O15245 (S22A1_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
415
Total Number of Articles : 473 |
Description |
solute carrier family 22 member 1 |
| Gene Summary |
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter. [provided by RefSeq, Jul 2008] |
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