Protein Name KIT ligand
Organism Homo sapiens
Gene ID 4254
Gene Symbol

KITLG

UniProt P21583 (SCF_HUMAN), A0A024RBC0 (A0A024RBC0_HUMAN), A0A024RBF5 (A0A024RBF5_HUMAN)
Relationships Total Number of functionally related compound(s) : 644
Total Number of Articles : 822
Description

KIT ligand

Gene Summary

This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

synonyms
  • kit ligand
  • c-Kit ligand
  • familial progressive hyperpigmentation 2
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Properties