Imatinib Mesylate

mitogen-activated protein kinase 3 ; Homo sapiens







29 Article(s)
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1 34504783 RanBP3 Regulates Proliferation, Apoptosis and Chemosensitivity of Chronic Myeloid Leukemia Cells via Mediating SMAD2/3 and ERK1/2 Nuclear Transport. 2021 1
2 30866043 Neferine in the Lotus Plumule Potentiates the Antitumor Effect of Imatinib in Primary Chronic Myeloid Leukemia Cells In Vitro. 2019 Apr 1
3 30504658 [MET/ERK and MET/JNK Pathway Activation Is Involved in BCR-ABL Inhibitor-resistance in Chronic Myeloid Leukemia]. 2018 1
4 28103766 Long-Term Exposure to Imatinib Mesylate Downregulates Hippo Pathway and Activates YAP in a Model of Chronic Myelogenous Leukemia. 2017 May 1 1
5 28418880 Contributions of MET activation to BCR-ABL1 tyrosine kinase inhibitor resistance in chronic myeloid leukemia cells. 2017 Jun 13 1
6 28927158 Regulation of HtrA2 on WT1 gene expression under imatinib stimulation and its effects on the cell biology of K562 cells. 2017 Sep 2
7 26919095 Inhibition of protein kinase CK2 by CX-5011 counteracts imatinib-resistance preventing rpS6 phosphorylation in chronic myeloid leukaemia cells: new combined therapeutic strategies. 2016 Apr 5 3
8 25182956 KIT and BRAF heterogeneous mutations in gastrointestinal stromal tumors after secondary imatinib resistance. 2015 Oct 2
9 23146907 Ableson kinases negatively regulate invadopodia function and invasion in head and neck squamous cell carcinoma by inhibiting an HB-EGF autocrine loop. 2013 Oct 1
10 22173128 C-Kit controls IL-1β-induced effector functions in HMC-cells. 2012 Jan 30 1
11 22327338 c-ABL modulates MAP kinases activation downstream of VEGFR-2 signaling by direct phosphorylation of the adaptor proteins GRB2 and NCK1. 2012 Jun 1
12 22798315 A critical role for p130Cas in the progression of pulmonary hypertension in humans and rodents. 2012 Oct 1 1
13 22875343 Raf/MEK/ERK signaling inhibition enhances the ability of dequalinium to induce apoptosis in the human leukemic cell line K562. 2012 Aug 1
14 20596710 Imatinib mesylate enhances the malignant behavior of human breast carcinoma cells. 2011 Apr 1
15 21152856 Selective inhibition of PDGFR by imatinib elicits the sustained activation of ERK and downstream receptor signaling in malignant glioma cells. 2011 Feb 1
16 21299849 BCR-ABL1-independent PI3Kinase activation causing imatinib-resistance. 2011 Feb 7 2
17 21727212 Nilotinib alone or in combination with selumetinib is a drug candidate for neurofibromatosis type 2. 2011 Jul 1
18 22096574 The colony-stimulating factor-1 (CSF-1) receptor sustains ERK1/2 activation and proliferation in breast cancer cell lines. 2011 1
19 19843070 Contribution of BCR-ABL-independent activation of ERK1/2 to acquired imatinib resistance in K562 chronic myeloid leukemia cells. 2010 Jan 7
20 20811709 Imatinib mesylate inhibits the proliferation-stimulating effect of human lung cancer-associated stromal fibroblasts on lung cancer cells. 2010 Oct 1
21 19225164 Preadipocyte apoptosis is prevented by macrophage-conditioned medium in a PDGF-dependent manner. 2009 Apr 1
22 18626307 Changes in pERK1/2 and pAKT expression in melanoma lesions after imatinib treatment. 2008 Aug 1
23 17495975 The novel tyrosine kinase inhibitor EXEL-0862 induces apoptosis in human FIP1L1-PDGFR-alpha-expressing cells through caspase-3-mediated cleavage of Mcl-1. 2007 Jul 1
24 17581316 Induction of urokinase-type plasminogen activator, interleukin-8 and early growth response-1 by STI571 through activating mitogen activated protein kinase in human small cell lung cancer cells. 2007 Jul 2
25 15094364 Role of E2F and ERK1/2 in STI571-mediated smooth muscle cell growth arrest and cyclin A transcriptional repression. 2004 May 14 3
26 15100154 Imatinib mesylate inhibits T-cell proliferation in vitro and delayed-type hypersensitivity in vivo. 2004 Aug 15 1
27 12850478 Involvement of Akt kinase in the action of STI571 on chronic myelogenous leukemia cells. 2003 Jul-Aug 1
28 12939459 Response markers and the molecular mechanisms of action of Gleevec in gastrointestinal stromal tumors. 2003 Aug 1
29 14555991 Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function. 2003 Oct 2 1