Camptothecin


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878 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 103
2 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 41
3 choline phosphotransferase 1 CHPT1_HUMAN CHPT1 Homo sapiens 56994 212 32
4 ATP binding cassette subfamily G member 2 (Junior blood group) ABCG2_HUMAN ABCG2 Homo sapiens 9429 1370 29
5 checkpoint kinase 1 CHK1_HUMAN CHEK1 Homo sapiens 1111 648 28
6 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 25
7 DNA topoisomerase I TOP1_HUMAN TOP1 Homo sapiens 7150 98 24
8 tyrosyl-DNA phosphodiesterase 1 TYDP1_HUMAN TDP1 Homo sapiens 55775 208 23
9 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 20
10 ATM serine/threonine kinase ATM_HUMAN ATM Homo sapiens 472 847 19
11 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 19
12 checkpoint kinase 2 CHK2_HUMAN CHEK2 Homo sapiens 11200 417 16
13 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 15
14 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 14
15 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 14
16 WRN RecQ like helicase WRN_HUMAN WRN Homo sapiens 7486 126 14
17 albumin ALBU_HUMAN ALB Homo sapiens 213 5631 13
18 ATR serine/threonine kinase ATR_HUMAN ATR Homo sapiens 545 866 11
19 cytochrome c, somatic CYC_HUMAN CYCS Homo sapiens 54205 3740 11
20 cyclin dependent kinase inhibitor 1A CDN1A_HUMAN CDKN1A Homo sapiens 1026 1631 11
21 TNF superfamily member 10 TNF10_HUMAN TNFSF10 Homo sapiens 8743 1439 11
22 BCL2 like 1 B2CL1_HUMAN BCL2L1 Homo sapiens 598 1360 10
23 MYC proto-oncogene, bHLH transcription factor MYC_HUMAN MYC Homo sapiens 4609 2261 10
24 topoisomerase (DNA) I TOP1_MOUSE Top1 Mus musculus 21969 54 10
25 H2A.X variant histone H2AX_HUMAN H2AX Homo sapiens 3014 412 9
26 replication protein A1 RFA1_HUMAN RPA1 Homo sapiens 6117 191 9
27 hypoxia inducible factor 1 subunit alpha HIF1A_HUMAN HIF1A Homo sapiens 3091 2152 9
28 MRE11 homolog, double strand break repair nuclease MRE11_HUMAN MRE11 Homo sapiens 4361 104 9
29 mitogen-activated protein kinase 8 MK08_HUMAN MAPK8 Homo sapiens 5599 2863 8
30 replication protein A2 RFA2_HUMAN RPA2 Homo sapiens 6118 52 8
31 Topoisomerase 1 TOP1_DROME Top1 Drosophila melanogaster 32458 6 8
32 transformation related protein 53, pseudogene - Trp53-ps Mus musculus 22060 1552 8
33 H3 histone pseudogene 16 - H3P16 Homo sapiens 644914 2095 7
34 caspase 8 CASP8_HUMAN CASP8 Homo sapiens 841 1641 7
35 host cell factor C1 HCFC1_HUMAN HCFC1 Homo sapiens 3054 516 7
36 annexin A5 ANXA5_HUMAN ANXA5 Homo sapiens 308 1785 7
37 Fas ligand TNFL6_HUMAN FASLG Homo sapiens 356 783 7
38 tyrosyl-DNA phosphodiesterase 1 TYDP1_YEAST TDP1 Saccharomyces cerevisiae S288C 852525 19 7
39 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 7
40 DNA topoisomerase 1 TOP1_CRIGR Top1 Cricetulus griseus 100689046 4 7
41 latexin LXN_HUMAN LXN Homo sapiens 56925 5329 7
42 cathepsin B CATB_HUMAN CTSB Homo sapiens 1508 1121 7
43 tumor protein p53 binding protein 1 TP53B_HUMAN TP53BP1 Homo sapiens 7158 156 6
44 caspase 3 CASP3_RAT Casp3 Rattus norvegicus 25402 2178 6
45 TNF receptor superfamily member 10b TR10B_HUMAN TNFRSF10B Homo sapiens 8795 608 6
46 nibrin NBN_HUMAN NBN Homo sapiens 4683 703 6
47 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 6
48 RecQ like helicase 5 RECQ5_HUMAN RECQL5 Homo sapiens 9400 17 6
49 mitogen-activated protein kinase 14 MK14_HUMAN MAPK14 Homo sapiens 1432 3132 6
50 RAD51 recombinase RAD51_HUMAN RAD51 Homo sapiens 5888 537 6