| Protein Name | DNA topoisomerase I |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 7150 |
| Gene Symbol | TOP1 |
| UniProt | P11387 (TOP1_HUMAN), Q9BVT2 (Q9BVT2_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
98
Total Number of Articles : 101 |
Description |
DNA topoisomerase I |
| Gene Summary |
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22. [provided by RefSeq, Jul 2008] |
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| Properties | |