| Protein Name | tyrosyl-DNA phosphodiesterase 1 |
|---|---|
| Organism | Saccharomyces cerevisiae S288C |
| Gene ID | 852525 |
| Gene Symbol | TDP1 |
| UniProt | P38319 (TYDP1_YEAST) |
| Relationships |
Total Number of functionally related compound(s) :
19
Total Number of Articles : 15 |
Description |
tyrosyl-DNA phosphodiesterase 1 |
| Gene Summary |
Enables 3'-tyrosyl-DNA phosphodiesterase activity and 5'-tyrosyl-DNA phosphodiesterase activity. Involved in DNA repair. Located in mitochondrion and nucleus. Used to study spinocerebellar ataxia type 1 with axonal neuropathy. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 1 with axonal neuropathy. Orthologous to human TDP1 (tyrosyl-DNA phosphodiesterase 1). [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |