| Protein Name | Topoisomerase 1 |
|---|---|
| Organism | Drosophila melanogaster |
| Gene ID | 32458 |
| Gene Symbol | Top1 |
| UniProt | P30189 (TOP1_DROME), Q494M1 (Q494M1_DROME), Q8IR39 (Q8IR39_DROME), X2JKD2 (X2JKD2_DROME), M9NDX3 (M9NDX3_DROME) |
| Relationships |
Total Number of functionally related compound(s) :
6
Total Number of Articles : 9 |
Description |
Topoisomerase 1 |
| Gene Summary |
Enables DNA topoisomerase type I (single strand cut, ATP-independent) activity. Involved in several processes, including DNA conformation change; instar larval development; and regulation of embryonic development. Located in chromosome; cytoplasm; and nucleolus. Is expressed in adult brain cell body rind; organism; and ovary. Orthologous to several human genes including TOP1 (DNA topoisomerase I). [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |