| Protein Name | topoisomerase (DNA) I |
|---|---|
| Organism | Mus musculus |
| Gene ID | 21969 |
| Gene Symbol | Top1 |
| UniProt | Q04750 (TOP1_MOUSE), Q3TPX7 (Q3TPX7_MOUSE), Q3ULF5 (Q3ULF5_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
54
Total Number of Articles : 56 |
Description |
topoisomerase (DNA) I |
| Gene Summary |
Enables DNA topoisomerase type I (single strand cut, ATP-independent) activity. Acts upstream of or within DNA replication; DNA topological change; and embryonic cleavage. Located in cytoplasm; nucleus; and perikaryon. Is expressed in brain; cerebral cortex ventricular layer; cortical plate; and telencephalon. Orthologous to human TOP1 (DNA topoisomerase I). [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |