| 1 |
32652764 | MIB1-mediated degradation of WRN promotes cellular senescence in response to camptothecin treatment. | 2020 Sep |
5 |
| 2 |
31114910 | RAD51 and mitotic function of mus81 are essential for recovery from low-dose of camptothecin in the absence of the WRN exonuclease. | 2019 Jul 26 |
1 |
| 3 |
26959889 | Camptothecin targets WRN protein: mechanism and relevance in clinical breast cancer. | 2016 Mar 22 |
4 |
| 4 |
26275776 | The WRN exonuclease domain protects nascent strands from pathological MRE11/EXO1-dependent degradation. | 2015 Nov 16 |
1 |
| 5 |
21786128 | Recapitulation of Werner syndrome sensitivity to camptothecin by limited knockdown of the WRN helicase/exonuclease. | 2012 Feb |
4 |
| 6 |
20516064 | Identification of a coiled coil in werner syndrome protein that facilitates multimerization and promotes exonuclease processivity. | 2010 Aug 13 |
1 |
| 7 |
18504617 | Sensitivity of RECQL4-deficient fibroblasts from Rothmund-Thomson syndrome patients to genotoxic agents. | 2008 Jul |
2 |
| 8 |
17917271 | Increased chemotherapeutic activity of camptothecin in cancer cells by siRNA-induced silencing of WRN helicase. | 2007 Oct |
3 |
| 9 |
16723399 | Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer. | 2006 Jun 6 |
1 |
| 10 |
15135730 | The Werner syndrome protein confers resistance to the DNA lesions N3-methyladenine and O6-methylguanine: implications for WRN function. | 2004 Jun 3 |
1 |
| 11 |
15149862 | Distinct functions for WRN and TP53 in a shared pathway of cellular response to 1-beta-D-arabinofuranosylcytosine and bleomycin. | 2004 Jun 10 |
1 |
| 12 |
12937274 | DNA damage modulates nucleolar interaction of the Werner protein with the AAA ATPase p97/VCP. | 2003 Oct |
1 |
| 13 |
11380620 | Werner helicase relocates into nuclear foci in response to DNA damaging agents and co-localizes with RPA and Rad51. | 2001 May |
3 |
| 14 |
10071186 | Werner syndrome lymphoblastoid cells are sensitive to camptothecin-induced apoptosis in S-phase. | 1999 Jan |
2 |